Chemistry:2-(Ethylamino)-1,2-diphenylethanone
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Short description: Chemical compound
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| Formula | C16H17NO |
| Molar mass | 239.318 g·mol−1 |
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2-(Ethylamino)-1,2-diphenylethanone (also known as α-ethylamino-deoxybenzoin, [α-(Ethylamino)benzyl]-(phenyl)-ketone and βk-Ephenidine) is a chemical compound which was first invented in 1955,[1] researched by ICI in 1969 as an antidepressant,[2] and subsequently claimed by AstraZeneca as an inhibitor of the enzyme 11β-Hydroxysteroid dehydrogenase type 1.[3] No other pharmacological data has been disclosed, though its chemical structure closely resembles that of certain designer drug compounds such as ephenidine and N-ethylhexedrone.
See also
References
- ↑ "Über α-Alkylamino-ketone.". Helvetica Chimica Acta 38 (6): 1415–1420. 1955. doi:10.1002/hlca.19550380613.
- ↑ Gilman DJ, "Desyl amines and compositions thereof. gdate = 19 February 1969", GB patent 1143263, assigned to ICI Ltd.
- ↑ Barton P, Clarke D, Davies C, Hargreaves R, Pease J, Rankine M, "Ketones", US patent Abandoned 2005272036, published 8 December 2005, assigned to AstraZeneca AB
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