Chemistry:Fluorolintane
From HandWiki
Short description: Chemical compound
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| Formula | C18H20FN |
| Molar mass | 269.363 g·mol−1 |
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Fluorolintane (also known as 2-FPPP and 2-F-DPPy) is a dissociative anesthetic drug that has been sold online as a designer drug.[1][2][3][4]
Fluorolintane and related diarylethylamines are antagonists of the NMDA receptor[5] and have been studied in vitro as potential treatments for neurotoxic injury,[6] depression[7] and as sympathomimetic.[8]
See also
References
- ↑ "Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers". Drug Testing and Analysis 7 (5): 358–367. May 2015. doi:10.1002/dta.1689. PMID 25044512. https://researchonline.ljmu.ac.uk/id/eprint/3408/1/DTA-14-0117.R1.pdf.
- ↑ "Analytical Report - Fluorolintane". Nacionalni forenzični laboratorij (NFL). January 2016. https://www.policija.si/apps/nfl_response_web/0_Analytical_Reports_final/FLUOROLINTANE-ID-1420-15-report_final.pdf.
- ↑ "Pharmacological characterizations of the 'legal high' fluorolintane and isomers". European Journal of Pharmacology 857: 172427. August 2019. doi:10.1016/j.ejphar.2019.172427. PMID 31152702.
- ↑ "Syntheses and analytical characterizations of the research chemical 1-[1-(2-fluorophenyl)-2-phenylethyl]pyrrolidine (fluorolintane) and five of its isomers". Drug Testing and Analysis 11 (8): 1144–1161. August 2019. doi:10.1002/dta.2608. PMID 31033229.
- ↑ "NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds". Bioorganic & Medicinal Chemistry 17 (9): 3456–62. May 2009. doi:10.1016/j.bmc.2009.03.025. PMID 19345586.
- ↑ "Patent EP 0346791 B1 - 1,2-diarylethylamines for treatment of neurotoxic injury". 1994. https://patents.google.com/patent/EP0346791B1.
- ↑ "Patent US 3083139 A - Therapeutic 1-(1, 2-diphenylethyl) pyrrolidine for the management of depression". 1963. https://patents.google.com/patent/US3083139.
- ↑ "Compounds Containing the Pyrrolidine Ring. Analogs of Sympathomimetic Amines". Journal of the American Chemical Society 75 (14): 3409–3413. July 1953. doi:10.1021/ja01110a033.
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