Chemistry:Dichlorophen
From HandWiki
Dichlorophen is an organochlorine compound with the formula CH
2(C
6H
3(OH)Cl)
2. In terms of molecular structure, it consists of two 4-chlorophenol groups linked by a methylene.[1]
It is anticestodal agent, fungicide, germicide, and antimicrobial agent.[2] It is used in combination with toluene for the removal of parasites such as ascarids, hookworms, and tapeworms from dogs and cats.[3] In 2025, dichlorophen was reported to function as a tubulin binding mitotic inhibitor.[4]
Safety and regulation
The -1">50 (oral, mouse) is 3300 mg/kg.[1]
References
- ↑ 1.0 1.1 "Ullmann's Encyclopedia of Industrial Chemistry". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. 2007. doi:10.1002/14356007.a19_313.
- ↑ Milne, G.W.A. (Ed.). (2005). Gardner's commercially important chemicals: Synonyms, trade names, and properties. Hoboken, N.J.: Wiley-Interscience. Google Books
- ↑ "Code of Federal Regulations", Code of Federal Regulations, Title 21, Volume 6 (U.S. Government Printing Office), 2005-04-01, http://frwebgate1.access.gpo.gov/cgi-bin/TEXTgate.cgi?WAISdocID=220114194717+2+1+0&WAISaction=retrieve, retrieved 2009-05-01
- ↑ "NanoDSF Screening for Anti-tubulin Agents Uncovers New Structure–Activity Insights". Journal of Medicinal Chemistry. 2025. doi:10.1021/acs.jmedchem.5c01008.
 |  |
