Chemistry:Fasinumab
From HandWiki
Short description: Monoclonal antibody
| Monoclonal antibody | |
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| Type | ? |
| Source | Human |
| Target | HNGF |
| Clinical data | |
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| ChemSpider |
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| Formula | C6406H9896N1700O2026S46 |
| Molar mass | 144618.27 g·mol−1 |
Fasinumab is a human monoclonal antibody designed for the treatment of acute sciatic pain.[1][2]
This drug was developed in collaboration by Teva Pharmaceutical Industries and Regeneron Pharmaceuticals.
It is currently at Phase III trials (NCT03245008, NCT02683239, and NCT03161093).[3]
See also
References
- ↑ "Fasinumab". Statement On A Nonproprietary Name Adopted By The USAN Council. American Medical Association. http://www.ama-assn.org/resources/doc/usan/fasinumab.pdf.
- ↑ "Fasinumab (REGN475), an antinerve growth factor monoclonal antibody, for the treatment of acute sciatic pain: results of a proof-of-concept study". Journal of Pain Research 7: 523–530. 2014. doi:10.2147/JPR.S65974. PMID 25210473.
- ↑ "Nerve Growth Factor (NGF) Inhibitors and Related Agents for Chronic Musculoskeletal Pain: A Comprehensive Review". BioDrugs 35 (6): 611–641. November 2021. doi:10.1007/s40259-021-00504-8. PMID 34807432.
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