Company:Teva Pharmaceutical Industries

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Teva Pharmaceutical Industries Ltd.
טבע תעשיות פרמצבטיות בע"מ
TypePublic
NYSE: TEVA
TASE: TEVA
IndustryPharmaceutical
Founded1901; 123 years ago (1901)
FounderDr. Günther Friedländer
Chaim Salomon
Moshe Levin
Yitschak Elstein
Headquarters
Petah Tikva
,
Israel
Key people
  • Kåre Schultz (President and CEO)
  • Sol Barer (Chairman)
  • Mike McClellan (Chief Financial Officer)
ProductsPharmaceuticals
RevenueIncrease US$ 22.385 billion (2017)
Increase US$ 2.165 billion (2016)
Increase US$ 327 Million (2016)
Number of employees
Template:Augmentation 51,792 (2017)
SubsidiariesTeva Canada
Websitewww.teva.co.il
www.tevapharm.com
Dr. Günther Friedländer founder of Teva Pharmaceutical Industries in Jerusalem

Teva Pharmaceutical Industries Ltd. (Hebrew: טבע תעשיות פרמצבטיות בע"מ) is an Israeli multinational pharmaceutical company headquartered in Petah Tikva, Israel.[1] It specializes primarily in generic drugs, but other business interests include active pharmaceutical ingredients and, to a lesser extent, proprietary pharmaceuticals. It is the largest generic drug manufacturer in the world[2] and one of the 15 largest pharmaceutical companies worldwide.[3]

Teva's facilities are located in Israel, North America, Europe, and South America. Teva shares trade on both the New York Stock Exchange (via ADRs) and the Tel Aviv Stock Exchange. The company is a member of the Pharmaceutical Research and Manufacturers of America (PhRMA).[4][5]

History

Worker at Assia plant in the 1930s
Teva plant, Har Hotzvim, Jerusalem
Teva in Markham, Ontario

Founding of "Salomon, Levin, and Elstein"

Teva's earliest predecessor was "Salomon, Levin, and Elstein Ltd.", a wholesale distributor based in Jerusalem, then part of Ottoman Syria, that was founded in 1901, and used camels to make deliveries.[6] During the 1930s, new immigrants from Europe founded several pharmaceutical companies including "Teva" ("Nature" in Hebrew) and "Zori". "Salomon, Levin, and Elstein Ltd." also found a pharmaceutical company in the 1930's named "Assia".

Funding of "Teva Pharmaceutical Industries"

"Teva Pharmaceutical Industries" was founded by Dr. Günther Friedländer and his aunt Else Kober, In May 1, 1935. The company's registered name at the time was: "Teva Middle East Pharmaceutical & chemical Works Co. Ltd. Jerusalem, Palestine". Friedländer was a German a pharmacist, botanist and pharmacognos, that immigrated to Mandatory Palestine in 1934, following the Nazi Party Rise to power.

The company was built with an investment of 4,900 pound sterling, which came from the familay's own capital and partly from loans from other German immigrants. Capital shortage lead to the joining of the banker Dr. Alfred Feuchtwanger as a partner in "Teva", who received 33% of the shares in return for his investment.[7] . In 1951, Dr. Feuchtwanger initiated an initial public offering to raise capitl through the newly founded Tel-Aviv Stock Exchange, and "Teva" became a public company.[8]

Friedländer used to say during difficult economic times, that a pharmaceutical industry has a strong basis in that: "A Jewish mother will always buy medicine for her children". In the Second World War, the company provided medicine to the allied forces and in particular to the British army present in the Middle East. After the war, Sir Alan Gordon Cunningham, the last High Commissioners for Palestine and Transjordan, visited "Teva" on behalf of the Secretary of State for the Colonies. His visit glorified Teva's reputation in the "Pharmaceutical market" and created a momentum for "Teva"'s development.

During the Second World War and until the termination of the British Mandatory Palestine regime, "Teva" exported its medical products to Arab countries. In 1941, Dr. Friedländer presented "Teva" company products in an exhibition held in Cairo, Egypt. The exhibition was sponsored by the "General Agent and Sole Distribution of medicine in Egypt and Sudan, Syria and Lebanon. Later on, "Teva" exported its products to the US, Soviet Union (USSR), health institutes in Denmark , Czechoslovakia, Persia and Burma.

In 1959, the Pharmaceutical branch of the "Israeli Manufacturer's Association" performed a survey grading the pharmaceutical companies in Israel according to several measures. "Teva Pharmaceuticals" of Jerusalem was graded in the first place. The survey results showed that the market prefers the "Teva" products, many of them were developed by Dr. Friedländer and his staff. In 1954, "Teva" received a "Certificate Excellence in Training" award from the Israeli President, Yitzhak Ben Zvi. Dr. Friedländer emphasized the importance of education and training of Teva personnel for the various operations, as demanded by the pharmaceutical industry, as well as on achieving broader knowledge and participation in various courses held outside the company. In 1964, a partnership between "Teva" and other companies was developed. These included, "Sintex" a company from Mexico, "Schering Plough" and others.

Merger of "Assia", "Zori" and "Teva"

In 1964, "Assia" and "Zori" merged and in 1968 acquired a controlling stake in "Teva". In 1976, the three companies merged into the modern-day "Teva Pharmaceutical Industries Ltd.". In 1980, Teva continued to follow its vision of becoming one of the world's biggest pharmaceutical companies by acquiring Ikapharm, then Israel's second largest drug manufacturer.[9]

In 1982, Teva was granted approval by the U.S. Food and Drug Administration (FDA) for its Kfar Saba manufacturing plant, an essential milestone for marketing pharmaceuticals in the US.[citation needed]

1980 to 1999

In 1980, Teva acquired Plantex.[10]

In 1995, Teva acquired Biogal Gyógyszergyár Rt. (Debrecen, Hungary) and acquired ICI (Italy)[11]

2000 to 2009

In 2000 Teva acquired Canada-based Novopharm.[12]

In October 2003, Teva announced its intentions to acquire Sicor Inc. for $3.4 billion[13]. Following the announcement, the acquisition was completed on January 22, 2004, which marked Teva's entry into biosimilars' market[14].

In 2005, Teva opened a new, state-of-the-art pharmaceutical manufacturing plant in Har Hotzvim, a technology park in Jerusalem. The plant received FDA approval in early 2007.[15] Teva entered the Japanese market in 2005, and in 2008 established a generics joint venture with Kowa.[16][17]

In January 2006, Teva said it had completed the acquisition of IVAX Corporation for $7.4 billion.[18][19]

In 2008, sales totalled $11.08 billion, $13.9 billion in 2009, and in 2010 total sales rose to $16.1 billion, of which a major portion was in Europe and North America. Teva acquired its U.S. rival Ivax Corporation in January 2006,[20][21] Barr in 2007 and Ratiopharm in 2010.On December 23, 2008, Teva acquired Barr Pharmaceuticals for $7.5 billion, making Barr and Pliva (which Barr bought earlier) part of Teva.[22]

2010 onwards

On March 18, 2010, Teva said it planned to acquire German generic Ratiopharm for US$5 billion. The deal was completed in August 2010.[15] In May 2011, Teva bought Cephalon for US$6.8 billion.[23] The same month, Teva announced the ¥40 billion purchase of a majority stake in Japanese generic drug company Taiyo Pharmaceutical Industry, a move to secure a Japan-local production facility.[16] Teva completed the $934 million acquisition in July 2011.[24] In June 2013 Teva acquired US firm MicroDose for $40 million with as much as $125 million being paid in regulatory and developmental milestones [25] In 2010, Teva announced that it would build its main distribution center for the Americas in Philadelphia, PA, and was considering opening its US headquarters in the area.[15] In 2010, it had 39,660 employees. In Israel, the number of workers rose 7.5% by 6,774.[26] In March 2010, Teva acquired German-based company Ratiopharm in a deal worth almost $5 billion, significantly expanding its European coverage.[27][28][29] In October 2010, Teva entered a licensing agreement with BioTime to develop and market BioTime's OpRegen for the treatment of age-related macular degeneration,[30] an effort that in 2013 received $1.5 billion in funding from Israel's Office of the Chief Scientist.[31]

In May 2011 Teva announced it would purchase Cephalon for US$6.8 billion, to help expand its presence in the proprietary pharmaceuticals sector.

In January 2014, Teva acquired NuPathe, after outbidding Endo, for $144 million.[32] In June 2014, Teva acquired Labrys Biologics for up to $825 million,[33] the aim being to strengthen the company's migraine pipeline through addition of LBR-101, an anti-CGRP monoclonal antibody therapeutic.[34]

In March 2015, Teva acquired Auspex Pharmaceuticals for $3.5 billion growing its CNS portfolio.[35] In April, Teva offered to acquire Mylan for $40 billion,[36] only a fortnight after Mylan offered to buy Perrigo for $29 billion.[37] Teva's offer for Mylan was contingent on Mylan abandoning its pursuit of Perrigo.[38] Mylan stated in June 2015 that Teva’s disclosure that it had a 1.35 percent stake in Mylan violated US anti-trust rules.[39] In October, the company acquired Mexico-based Representaciones e Investigaciones Medicas (Rimsa) for around $2.3 billion.[40] In the same month Teva acquired Gecko Health Innovations.[41] In November 2015, the company announced it would collaborate with Heptares Therapeutics with its work on small-molecule calcitonin gene-related peptide antagonists for migraine treatment, with the deal generating up to $410 million.[42]

Teva Active Pharmaceutical Ingredients (TAPI) operates within Teva as a stand-alone business unit. As well as providing for Teva's own needs, the TAPI division is an active competitor in world markets. In 2009, TAPI's sales to third parties totaled $565 million, and in 2010 sales rose by 13% to a total of $641 million.[citation needed]

In July 2017, it was reported that Pascal Soriot, CEO of AstraZeneca since 2012, would become the next CEO of Teva, succeeding Erez Vigodman,[43][44] however this was soon refuted.[45] As of August 2017, the company has struggled to attract a new CEO, leading to mounting questions for the board.[46] In August 2017, the board of directors announced a 75% cut in the dividend, reflecting declining profitability, and the share price fell by almost half in the days following.[47][48] As of September 11, 2017, Teva remained the “world’s biggest seller of generics medicines.” On September 11, 2017, it was reported that they had selected Kåre Schultz as the new Teva CEO.[49] A day later the company announced it would sell its Paragard contraceptive brand to Cooper Cos for $1.1 billion, with the funds being used to pay down debt.[50] Days later the company announced further divestments: a sale of contraception, fertility, menopause and osteoporosis products to CVC Capital Partners Fund VI for $703 million and its emergency contraception brands for $675 million to Foundation Consumer Healthcare.[51] By December, the company had announced a drastic twenty-five percent workforce reduction (>14,000 employees) as part of a two-year cost-reduction strategy.[52] Following considerable lobbying by the Israeli Government, from whom Teva received considerable tax breaks[53], and from Israel's labor federation, the Histadrut, Teva agreed to delay some of the layoffs in Israel[54]

Actavis Generics

In July 2015, Allergan agreed to sell its generic drug business (Actavis Generics[55]) to Teva for $40.5 billion[56][57][58] ($33.75 billion in cash and $6.75 billion worth of shares).[59] As a result, Teva dropped its pursuit of Mylan. In order for the deal to gain regulatory approval, Teva sold off a number of assets, including a portfolio of five generic drugs to Sagent Pharmaceuticals for $40 million, as well as a further eight medicines to Dr. Reddy’s in a $350 million deal.[55] Teva also sold a further 15 marketed generics, as well as three others which were close to market, for $586 million to Impax Laboratories.[60][61] In July, Teva sold off a further 42 products to Australian generics company, Mayne Pharma, for $652 million; the deal moved Mayne up 50 spots, into the top-25 companies of US generic companies.[62] As part of the deal Teva will seek to raise $20 to $25 billion[63] through a bond sale.[64]

After completing the $39 billion acquisition of Actavis Generics, Teva announced another, smaller, deal with Allergan, agreeing to acquire its generic distribution business Anda for $500 million.[65]

Acquisition history

The following is an illustration of the company's major mergers and acquisitions and historical predecessors (this is not a comprehensive list):

Teva Pharmaceutical Industries
 

Gecko Health Innovations
(Acq 2015)

 
 
 

Rimsa
(Acq 2015)

 
 
 

Actavis Generics
(Generic drug div Allergan, plc, Acq 2015)

 
 
 

Auspex Pharmaceuticals
(Acq 2014)

 
 
 

Labrys Biologics
(Acq 2014)

 
 
 

NuPathe after
(Acq 2014)

 
 
 

MicroDose
(Acq 2013)

 
 
 

Taiyo Pharmaceutical Industry
(Acq 2011)

 
 
Cephalon
(Acq 2011)
 

Arana Therapeutics
(Acq 2009)

 
 
 

ChemGenex Pharmaceuticals
(Acq 2011)

 
 
 
 
 

Ratiopharm
(Acq 2010)

 
 
 

Barr Pharmaceuticals
(Acq 2008)

 
 
 

IVAX Corporation
(Acq 2006)

 
 
 

Novopharm
(Acq 2000)

 
 
 

Plantex
(Acq 1980)

 
 
 

Ikapharm
(Acq 1980)

 
 
 

Salomon, Levin, and Elstein Ltd
(Merged 1976 to form Teva Pharmaceutical Industries Ltd)

 
 

Assia
(Merged 1976 to form Teva Pharmaceutical Industries Ltd)

 
 

Zori
(Merged 1976 to form Teva Pharmaceutical Industries Ltd)

 
 
 

Glaxo
(Acq 1914)

 
 

Margarine Unie
(Acq 1924)

 
 

Allen & Hanburys
(Merged 1976 to form Teva Pharmaceutical Industries Ltd)

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Corporate governance

Chief Executive Officer Period of office Notes
Eli Hurvitz 1976 to 2002 CEO & Chairman of the board until his death in 2011.[66][67]
Israel Makov 2002 to 2007 [68][69]
Shlomo Yanai March 2007 to May 2012 Announced his resignation at the beginning of 2012.[70]
Jeremy Levin May 2012 to October 2013 [71]
Eyal Desheh October 2013 to January 2014 Interim CEO
Erez Vigodman January 2014 to February 2017 Desheh returned to previous position of chief financial officer.[72][73][74] Vigodman served as the CEO of Makhteshim Agan until joining Teva, and was President and CEO of Strauss Group prior to this.[74] From 2014, Michael Hayden served as Teva's chief scientific officer and president of the company's global research and development.[34]
Yitzhak Peterburg February 2017 to Sept 2017 Peterburg held the position of Chairman since 2015. He was appointed as Interim President and CEO in 2017 succeeding Erez Vigodman. Since Israeli law does not permit the same individual to serve as CEO and Chairman, Sol J Barer took over as the Chairman of the board in February 2017.[75]
Kåre Schultz[49] September 2017 – present Schultz was appointed as the CEO and President succeeding the acting President and CEO Yitzhak Peterburg.[76][77]

Research and development

Copaxone, a Teva patented drug

Teva holds patents on multiple drugs, including: Copaxone, a specialty drug[78] (for the treatment of multiple sclerosis), now the world's best selling MS drug,[79] and Azilect (sold as Agilect in some countries) for treatment of Parkinson's disease. By July 2015 Copaxone held a "31.2 percent shares of total MS prescriptions in the United States."[79] Teva's new 40 mg version of Copaxone taken three times a week "accounted for 68.5 percent of total Copaxone prescriptions in the United States."[79] Copaxone accounts for about fifty percent of "Teva's profit and 20 percent of revenue."[79] Competitors' Glatopa, 20 mg version of Copaxone, is taken once a day.[79]

In June 2006, Teva received from the FDA a 180-day exclusivity period to sell simvastatin (Zocor) in the U.S. as a generic drug in all strengths except 80 mg. Teva presently[when?] competes with the maker of brand-name Zocor, Merck & Co.; Ranbaxy Laboratories, which has 180-day exclusivity for the 80 mg strength; and Dr. Reddy's Laboratories, whose authorized generic version (licensed by Merck) is exempt from exclusivity.

In June 2010, the company announced it would discontinue its production of propofol, a major sedative estimated to be used in 75% of all US anesthetic procedures.[80]

In March 2015 Teva sold four anti-cancer compounds to Ignyta Inc. for $41.6 million. As part of the deal Teva sold the following compounds which were then renamed:[81]

  • CEP-32496 (renamed RXDX-105) a small molecule inhibitor of BRAF, EGFR and RET, now in Phase I/II trials
  • CEP-40783 (renamed RXDX-106) a small molecule inhibitor of AXL and c-Met in preclinical development
  • CEP-40125 (renamed RXDX-107) a nanoformulation of a modified bendamustine with potenital activity in solid tumours. Bendamustine Rapid Infusion as therapy for CLL and NHL is part of Teva's specialty drugs pipeline.[78]
  • TEV-44229 (renamed RXDX-108) a potent inhibitor of the kinase PKCiota

Legal issues

On June 25, 2010, Bayer sued Teva for falsely claiming that Gianvi, Teva's Generic of Yaz, was "stabilized by betadex as a clathrate."[82] The lawsuit stems from Bayer's US patent, 5798338, on the binding and preservative agents that were not in fact present in Gianvi. "In the preparation of such low-dosed dosage forms, strong fluctuations of the active ingredient concentrations in the dosage units occur almost unavoidably (inadequate content uniformity), which manifest themselves more strongly, the smaller the amount of the active ingredient. It has now been found that the drawbacks that are observed especially in the preparation and storage of dosage forms which contain low-dosed steroidal sex hormones can be avoided, at least to a large extent, if dosage forms are prepared that contain powdery cyclodextrin clathrates of these active ingredients."[83] The settlement of the lawsuit resulted in Teva changing its product marketing to remove the claim that it used the same ingredients as Yaz.[84][|permanent dead link|dead link}}] Bayer's patent is on a method specifically designed to prevent oxidative degradation of the estrogen.

In January 2015, the Supreme Court of the United States decided on the Copaxone patent in Teva Pharmaceuticals USA, Inc. v. Sandoz, Inc..[85]

In December 2016, the attorneys general of 20 states filed a civil complaint accusing Teva Pharmaceutical of a coordinated scheme to artificially maintain high prices for a generic antibiotic and diabetes drug. The complaint alleged price collusion schemes between six pharmaceutical firms including informal gatherings, telephone calls, and text messages.[86]

Pharmaceutical products

A full list of products is available from www.tevagenerics.com.


See also

  • Economy of Israel
  • Science and technology in Israel
  • Health care in Israel
  • BioTime
  • Teva Active Pharmaceutical Ingredients (TAPI)

References

  1. ↑ "TEVA PHARMACEUTICAL INDUSTRIES LIMITED | Israel Company Reports - Search Israeli Companies". https://www.israelbizreg.com/teva-pharmaceutical-industries-limited. 
  2. ↑ Hollis, Liz Jones (August 10, 2010). "Teva – Top 10 Generic Drug Companies 2010". FiercePharma. Washington, DC, United States: FierceMarkets. Archived from the original on May 8, 2011. https://www.webcitation.org/5yXPMLkBa?url=http://www.fiercepharma.com/special-reports/top-10-generic-drug-companies-2010/teva-top-10-generic-drug-companies-2010. Retrieved November 3, 2010. 
  3. ↑ "Teva Pharmaceutical Industries—Jerusalem". Database. Jerusalem, Israel: BioJerusalem. Archived from the original on July 21, 2011. https://web.archive.org/web/20110721143023/http://www.biojerusalem.org.il/database_company.asp?ID=76. 
  4. ↑ "Teva wins controversial PhRMA bid despite protests from branded rivals - FiercePharma". http://www.fiercepharma.com/pharma/teva-wins-controversial-phrma-bid-despite-protests-from-branded-rivals. Retrieved May 23, 2017. 
  5. ↑ "Teva, one of the biggest generic makers, joins the brand-name club". 18 July 2016. https://www.statnews.com/pharmalot/2016/07/18/teva-generics-phrma/. Retrieved 20 August 2017. 
  6. ↑ Kiliç, Burcu (July 31, 2014). "Boosting Pharmaceutical Innovation in the Post-TRIPS Era". Edward Elgar Publishing. https://books.google.com/books?id=L0gjBAAAQBAJ&pg=PA173&lpg=PA173&dq=teva+delivering+drugs+on+camel&source=bl&ots=2iE8nYsw1l&sig=MLEMnGt_jt9rs5YN21bAreHkF-Y&hl=en&sa=X&ved=0ahUKEwiWrtCfq-zSAhUqKcAKHTuJCFYQ6AEIMzAE#v=onepage&q=teva+delivering+drugs+on+camel&f=false. Retrieved May 23, 2017. 
  7. ↑ Alfred Feuchtwanger
  8. ↑ Kiliç, Burcu (July 31, 2014). "Boosting Pharmaceutical Innovation in the Post-TRIPS Era". Edward Elgar Publishing. https://books.google.com/books?id=L0gjBAAAQBAJ&pg=PA173&lpg=PA173&dq=teva+delivering+drugs+on+camel&source=bl&ots=2iE8nYsw1l&sig=MLEMnGt_jt9rs5YN21bAreHkF-Y&hl=en&sa=X&ved=0ahUKEwiWrtCfq-zSAhUqKcAKHTuJCFYQ6AEIMzAE#v=onepage&q=teva+delivering+drugs+on+camel&f=false. Retrieved May 23, 2017. 
  9. ↑ "Archived copy". Archived from the original on March 17, 2007. https://web.archive.org/web/20070317230702/http://www.tevapharm.com/about/history.asp. Retrieved 2007-03-17.  The History of Teva
  10. ↑ "Teva — Plantex Limited". tapi.com. http://www.tapi.com/About-US/WorldWide/Pages/PlantexLtd.aspx. 
  11. ↑ "Publish". http://www.tevapharm.com/about/history/. 
  12. ↑ "TEVA NOVOPHARM — Novopharm Limited becomes Teva Canada Limited". newswire.ca. http://www.newswire.ca/en/story/626423/novopharm-limited-becomes-teva-canada-limited. 
  13. ↑ Jerry Hirsch (1 November 2003). "Drug Maker Teva to Buy Sicor". Los Angeles Times. http://articles.latimes.com/2003/nov/01/business/fi-sicor1. 
  14. ↑ "Teva Completes Acquisition of Sicor". 22 January 2004. http://www.tevapharm.com/news/teva_completes_acquisition_of_sicor_01_04.aspx. 
  15. ↑ 15.0 15.1 15.2 Singer, Natasha (March 18, 2010). "Teva to Acquire Top German Generics Maker for $5 Billion". The New York Times. https://www.nytimes.com/2010/03/19/business/global/19drugs.html. Retrieved March 18, 2010. 
  16. ↑ 16.0 16.1 Grogan, Kevin (May 5, 2011). "Teva plans $500 million Japan acquisition". PharmaTimes Magazine (London, England): Online PharmaTimes. Archived from the original on May 7, 2011. https://www.webcitation.org/5yVp5Pr7b?url=http://www.pharmatimes.com/Article/11-05-05/Teva_plans_500_million_Japan_acquisition_-_Nikkei.aspx. Retrieved May 7, 2011. 
  17. ↑ "Kowa, Teva to form generic drug venture". 25 September 2008. https://www.japantimes.co.jp/news/2008/09/25/business/kowa-teva-to-form-generic-drug-venture/. Retrieved 20 August 2017. 
  18. ↑ "Archived copy". Archived from the original on November 7, 2014. https://web.archive.org/web/20141107105957/http://www.tevapharm.com/media/news/pages/2006/1557278.aspx. Retrieved 2014-11-07. 
  19. ↑ Schmit, Julie (July 26, 2005). "USATODAY.com — Teva Pharmaceuticals to buy Ivax in $7.4 billion deal". usatoday.com. http://usatoday30.usatoday.com/money/industries/health/drugs/2005-07-25-teva-ivax_x.htm. 
  20. ↑ Jennifer Bayot for the New York Times. July 26, 2005 Teva to Acquire Ivax, Another Maker of Generic Drugs
  21. ↑ Teva Press Release, 2006. Teva Completes Acquisition of Ivax
  22. ↑ "Teva Completes Acquisition of Barr". tevapharm.com. Archived from the original on January 24, 2009. https://web.archive.org/web/20090124234703/http://tevapharm.com/pr/2008/pr_813.asp. 
  23. ↑ Nicholson, Chris V. (May 2, 2011). "Teva to Buy Cephalon for $6.8 Billion". The New York Times. https://dealbook.nytimes.com/2011/05/02/teva-to-buy-cephalon-for-6-8-billion/?partner=rss&emc=rss. 
  24. ↑ Teva completes $934m Taiyo acquisition, Globes, 14 July 11
  25. ↑ David Wainer (June 17, 2013). "Teva Adds MicroDose to Respiratory Business in $165 Million Deal". Bloomberg.com. https://www.bloomberg.com/news/2013-06-17/teva-adds-microdose-to-respiratory-business-in-165-million-deal.html. 
  26. ↑ Yeshayahou, Koby (February 16, 2011). "Teva employees gain $222m on options". Globes (Rishon Le-Zion, Israel: Globes Publisher Itonut): globes-online.com. Archived from the original on May 8, 2011. https://www.webcitation.org/5yXQENLt8?url=http://www.globes.co.il/serveen/globes/docview.asp?did=1000623808&fid=1725. 
  27. ↑ Jonathan D. Rockoff; Eyk Henning (March 19, 2010). "Teva to Acquire Generics Firm" (~100 words). The Wall Street Journal (New York City): WSJ.com. Archived from the original on May 9, 2011. https://www.webcitation.org/5yXX2YMH8?url=http://online.wsj.com/article/SB10001424052748704207504575129240833529842.html. Retrieved May 8, 2011. 
  28. ↑ Robert Daniel; Polya Lesova (March 18, 2010). "Teva to acquire Ratiopharm in deal valued near $5 billion". MarketWatch. New York City: Dow Jones & Co.. Archived from the original on May 9, 2011. https://www.webcitation.org/5yXXk8ZU2?url=http://www.marketwatch.com/story/teva-near-478-bln-deal-for-ratiopharm-reports-2010-03-18. Retrieved May 8, 2011. 
  29. ↑ "Cell Cure Neurosciences Ltd., a Subsidiary of BioTime, Inc. and Hadasit Bio Holdings Ltd., Enters into an Exclusive License Option Agreement with Teva Pharmaceutical Industries Ltd.". http://www.businesswire.com/news/home/20101010005096/en/Cell-Cure-Neurosciences-Ltd.-Subsidiary-BioTime-Hadasit. 
  30. ↑ "BioTime’s Subsidiary Cell Cure Neurosciences Ltd. Awarded $1.5 Million Grant from Israel’s Office of the Chief Scientist". http://www.businesswire.com/news/home/20130513005575/en/BioTime%E2%80%99s-Subsidiary-Cell-Cure-Neurosciences-Ltd.-Awarded. 
  31. ↑ "Teva Outbids Endo, Acquires NuPathe for $144M+". Gen. Eng. Biotechnol. News 34 (4): p. 10. February 15, 2014. 
  32. ↑ Staff (June 3, 2014). "Teva Buys Labrys, Growing Pain Franchise in Up to $825M Deal". Genetic Engineering & Biotechnology News. http://www.genengnews.com/gen-news-highlights/teva-buys-labrys-growing-pain-franchise-in-up-to-825m-deal/81249936/. Retrieved July 21, 2014. 
  33. ↑ 34.0 34.1 George, John (July 21, 2014). "Teva completes deal for second migraine-treatment developer". Philadelphia Business Journal. http://www.bizjournals.com/philadelphia/blog/health-care/2014/07/teva-completes-deal-for-second-migrainetreatment.html. Retrieved July 21, 2014. 
  34. ↑ Staff (March 30, 2015). "Teva to Acquire Auspex for $3.5B, Growing CNS Portfolio". Genetic Engineering & Biotechnology News. http://www.genengnews.com/gen-news-highlights/teva-to-acquire-auspex-for-3-5b-growing-cns-portfolio/81251086/. Retrieved April 21, 2015. 
  35. ↑ Staff (April 21, 2015). "Teva Offers to Buy Mylan for $40B". Genetic Engineering & Biotechnology News. http://www.genengnews.com/gen-news-highlights/teva-offers-to-buy-mylan-for-40b/81251178/. Retrieved April 21, 2015. 
  36. ↑ Staff (April 8, 2015). "Mylan Offers $28.9B for Perrigo". Genetic Engineering & Biotechnology News. http://www.genengnews.com/gen-news-highlights/mylan-offers-28-9b-for-perrigo/81251129/. Retrieved April 21, 2015. 
  37. ↑ "Teva Offers to Buy Mylan in $40.1B Cash-And-Stock Deal". Pharmaceutical Processing. Associated Press. April 21, 2015. http://www.pharmpro.com/news/2015/04/teva-offers-buy-mylan-401b-cash-and-stock-deal?et_cid=4527542&et_rid=280926499&location=top. Retrieved April 21, 2015. 
  38. ↑ Anjali Rao Koppala (1 June 2015). "Mylan says Teva's stake buy violates U.S. anti-trust rules". Reuters. https://www.reuters.com/article/2015/06/01/us-mylan-m-a-teva-pharm-ind-idUSKBN0OH3H520150601. Retrieved 2 June 2015. 
  39. ↑ "Teva beefs up in emerging markets with $2.3B Rimsa buyout - FiercePharma". http://www.fiercepharma.com/story/teva-beefs-emerging-markets-23b-rimsa-buyout/2015-10-01. 
  40. ↑ "Teva snaps up Gecko and its 'smart inhaler' to pump up respiratory meds - FiercePharma". http://www.fiercepharmamarketing.com/story/teva-snaps-gecko-and-its-smart-inhaler-pump-respiratory-meds/2015-10-05. 
  41. ↑ "Teva, Heptares Launch Up-to-$410M+ Migraine Alliance - GEN News Highlights - GEN". http://www.genengnews.com/gen-news-highlights/teva-heptares-launch-up-to-410m-migraine-alliance/81252024/. 
  42. ↑ Reuters Editorial (2014-05-14). "AstraZeneca's CEO Soriot to join Israeli drugs company Teva: report". Reuters. https://www.reuters.com/article/us-teva-pharm-ind-astrazeneca-ceo-idUSKBN19X2OB?il=0. Retrieved 2017-07-12. 
  43. ↑ "Israeli newspaper reports that AstraZeneca CEO Pascal Soriot has agreed to take the helm at Teva – ENDPOINTS NEWS". Endpts.com. https://endpts.com/israeli-newspaper-reports-that-astrazeneca-ceo-pascal-soriot-has-agreed-to-take-the-helm-at-teva/. Retrieved 2017-07-12. 
  44. ↑ Boland, Hannah. "Pascal Soriot looks set to stay as AstraZeneca chief". The Daily Telegraph. https://www.telegraph.co.uk/business/2017/07/14/pascal-soriot-looks-set-stay-astrazeneca-chief/. Retrieved May 15, 2018. 
  45. ↑ Jones, Rory (7 Aug 2017). "Teva Pharmaceutical Industries faces high price for new chief". The Wall Street Journal. http://www.theaustralian.com.au/business/wall-street-journal/teva-pharmaceutical-industries-faces-high-price-for-new-chief/news-story/49f6127a1fd8ca5c809bdf7be9a4193b. Retrieved 6 August 2017. 
  46. ↑ Teva (3 August 2017). "Press Release: Teva Reports Second Quarter 2017 Financial Results". http://phx.corporate-ir.net/External.File?item=UGFyZW50SUQ9Mzg1MTE3fENoaWxkSUQ9LTF8VHlwZT0z&t=1&cb=636373238980296840. Retrieved 8 August 2017. 
  47. ↑ "Teva stock price chart". https://www.google.com/finance?q=NYSE:TEVA. Retrieved 8 August 2017. 
  48. ↑ 49.0 49.1 Rory Jones (September 11, 2017). "Teva Appoints New Chief Executive After Months of Speculation". Wall Street Journal (New York City, New York, United States). https://www.wsj.com/articles/teva-names-kare-schultz-as-new-chief-executive-1505115189. 
  49. ↑ http://uk.reuters.com/article/us-teva-pharm-ind-divestiture-contracept/teva-to-sell-contraceptive-brand-paragard-in-1-1-billion-deal-idUKKCN1BM2KQ
  50. ↑ http://www.fiercepharma.com/m-a/teva-finishes-women-s-health-sale-deals-worth-1-38b
  51. ↑ Barber, Joe (December 14, 2017). "Teva to cut over 25 percent of global workforce". First Word Pharma Plus (Doctor's Guide Publishing Limited). https://www.firstwordpharma.com/node/1530082. 
  52. ↑ Schindler, Max (December 22, 2017). "ECONOMY MINISTER: TEVA SHOULD EARN ITS TAX BREAKS". http://www.jpost.com/Israel-News/Economy-minister-Teva-should-earn-its-tax-breaks-519754. 
  53. ↑ Weinreb, Gali (January 1, 2018). "TEVA DELAYS 33% OF JERUSALEM LAYOFFS UNTIL 2019". http://www.jpost.com/Israel-News/Teva-delays-33-percent-of-Jerusalem-layoffs-until-2019-522541. 
  54. ↑ 55.0 55.1 "Analyst cuts Allergan generics sales estimates as Teva deal close nears - FiercePharma". http://www.fiercepharma.com/pharma/analyst-cuts-allergan-generics-sales-estimates-as-teva-deal-close-nears. 
  55. ↑ "Teva to Buy Allergan's Generic Drug Unit". Bloomberg.com. July 27, 2015. https://www.bloomberg.com/news/videos/2015-07-27/teva-to-buy-allergan-s-generic-drug-unit. 
  56. ↑ Cynthia Koons (July 27, 2015). "Teva CEO: $40.5 Billion Allergan Deal is Just the Beginning - Bloomberg Business". Bloomberg.com. https://www.bloomberg.com/news/articles/2015-07-27/teva-ceo-sees-more-deals-coming-after-40-5b-allergan-purchase. 
  57. ↑ "Teva Purchasing Allergan's Generics Unit in $40.5B Deal". Bloomberg.com. July 27, 2015. https://www.bloomberg.com/news/videos/2015-07-27/teva-purchasing-allergan-s-generics-unit-in-40-5b-deal. 
  58. ↑ Chitra Somayaji (July 27, 2015). "Teva Snaps Up Allergan’s Generics Arm, Dumping Mylan". Bloomberg.com. https://www.bloomberg.com/news/articles/2015-07-27/teva-snaps-up-allergan-s-generics-arm-dumping-mylan. 
  59. ↑ "Impax Buys Generic Product Portfolio from Teva, Allergan for $586M - GEN News Highlights - GEN". http://www.genengnews.com/gen-news-highlights/impax-buys-generic-product-portfolio-from-teva-allergan-for-586m/81252854/. 
  60. ↑ "Teva sells castoffs to Impax for $586M as clock ticks on Allergan deal - FiercePharma". http://www.fiercepharma.com/pharma/teva-sells-cast-offs-to-impax-for-586m-as-clock-ticks-allergan-deal. 
  61. ↑ "Mayne vaults ahead in U.S. with $652M deal for Teva/Allergan meds - FiercePharma". http://www.fiercepharma.com/pharma/mayne-scoops-up-42-meds-from-teva-allergan-652m-deal. 
  62. ↑ "Teva looks for $20B-plus from bond sale to finance Allergan deal - FiercePharma". http://www.fiercepharma.com/pharma/teva-looks-for-20b-plus-from-bond-sale-to-finance-allergan-deal. 
  63. ↑ "Form 6-K". https://www.sec.gov/Archives/edgar/data/818686/000119312516647185/d220417d6k.htm. 
  64. ↑ "After Completing $39B Acquisition, Teva Does Another Generics Deal with Allergan - GEN Genetic Engineering & Biotechnology News - Biotech from Bench to Business - GEN". http://www.genengnews.com/gen-news-highlights/after-completing-39b-acquisition-teva-does-another-generics-deal-with-allergan/81253042/. Retrieved May 23, 2017. 
  65. ↑ "Teva Pharmaceutical Industries Ltd (TEVA.O) Officers". Reuters. Archived from the original on September 29, 2008. https://web.archive.org/web/20080929214726/https://www.reuters.com/finance/stocks/officerProfile?symbol=TEVA.O&officerId=132712. Retrieved October 11, 2008. 
  66. ↑ Coren, Ora (February 21, 2008). "Most respected managers in market: Tshuva, Dankner, Maor and Hurvitz". Haaretz. Archived from the original on October 20, 2012. https://web.archive.org/web/20121020133703/http://www.haaretz.com/print-edition/business/most-respected-managers-in-market-tshuva-dankner-maor-and-hurvitz-1.239727. Retrieved March 21, 2014. 
  67. ↑ Teva Pharmaceuticals Inc. (February 14, 2002). "Teva news release hiring Israel Makov". http://ir.tevapharm.com/phoenix.zhtml?c=73925&p=irol-newsArticle_Print&ID=1556547&highlight=. Retrieved September 28, 2014. 
  68. ↑ Golan Hazani. (October 18, 2006). "Ynet reports Israel Makov resignation". http://www.ynetnews.com/articles/1,7340,L-3316626,00.html. Retrieved September 28, 2014. 
  69. ↑ "Teva CEO Shlomo Yanai leaving in May, to be replaced by American". Haaretz. http://www.haaretz.com/business/teva-ceo-shlomo-yanai-leaving-in-may-to-be-replaced-by-american-1.405070. Retrieved December 7, 2013. 
  70. ↑ "Teva CEO Jeremy Levin steps down". Globes. Archived from the original on November 4, 2013. https://web.archive.org/web/20131104152001/http://www.globes.co.il/serveen/globes/docview.asp?did=1000889846. Retrieved October 30, 2013. 
  71. ↑ "Teva Names a New Chief Executive". The New York Times. Bloomberg News. January 2, 2012. Archived from the original on April 27, 2012. https://web.archive.org/web/20120427040309/http://www.nytimes.com/2012/01/03/business/teva-names-a-new-chief-executive.html. Retrieved January 3, 2012. (registration required)
  72. ↑ "Israel's Teva Pharm names Vigodman as CEO". Reuters. January 9, 2014. Archived from the original on January 9, 2014. https://web.archive.org/web/20140109120239/https://www.reuters.com/article/2014/01/09/tevapharm-ceo-idUSL6N0KJ0LT20140109. 
  73. ↑ 74.0 74.1 "People". Gen. Eng. Biotechnol. News 34 (4): p. 41. February 15, 2014. 
  74. ↑ "Teva Appoints Dr. Yitzhak Peterburg as Interim Chief Executive Officer, Succeeding Erez Vigodman". https://teva-actavis.newsweaver.com/icfiles/2/77531/173109/163545/e83b65116c42e31302eb3c08/teva%20management%20change%20prfinal_4.pdf. 
  75. ↑ Jones, Rory (2017-09-11). "Teva Appoints New Chief Executive After Months of Speculation" (in en-US). Wall Street Journal. ISSN 0099-9660. https://www.wsj.com/articles/teva-names-kare-schultz-as-new-chief-executive-1505115189. 
  76. ↑ Scheer, Steven; Jacobsen, Stine (September 11, 2017). "Drugmaker Teva hires Lundbeck CEO Schultz to restore its health". Reuters. https://www.reuters.com/article/us-teva-pharm-ind-ceo/israels-teva-pharma-appoints-h-lundbecks-kare-schultz-as-ceo-idUSKCN1BM0LU. Retrieved 2017-09-12. 
  77. ↑ 78.0 78.1 "Our Specialty Pipeline". Teva Pharmaceutical Industries. nd. http://www.tevapharm.com/research_development/rd_focus/pipeline/. Retrieved 16 October 2015. 
  78. ↑ 79.0 79.1 79.2 79.3 79.4 "Teva's MS drug Copaxone has strong second-quarter sales". Reuters. Jerusalem, Israel. July 2015. https://www.reuters.com/article/2015/07/30/teva-pharm-ind-results-idUSL5N10A3VA20150730. Retrieved 16 October 2015. 
  79. ↑ "Teva won't make more of powerful sedative". http://www.msnbc.msn.com/id/37403276/ns/health-health_care/. 
  80. ↑ "GEN — News Highlights:Ignyta Buys Four Cancer Compounds from Teva". GEN. http://www.genengnews.com/gen-news-highlights/ignyta-buys-four-cancer-compounds-from-teva/81251046/. 
  81. ↑ Bayer HealthCare Pharmaceuticals Inc. (June 25, 2010). "Bayer Sues Teva and Barr for False Advertising and Patent Infringement in Connection with Teva’s Generic Oral Contraceptive Gianvi". Archived from the original on January 3, 2011. https://web.archive.org/web/20110103015518/http://pharma.bayer.com/scripts/pages/en/news_room/news_room/news_room95.php. Retrieved December 26, 2010. 
  82. ↑ Backensfeld (August 25, 1998). "Solid dosage forms that contain clathrates of 17.alpha.-ethinyl estradiol". http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=5798338.PN.&OS=PN/5798338&RS=PN/5798338. Retrieved December 26, 2010. 
  83. ↑ Maureen M Cavanaugh, Teva Pharmaceuticals (July 1, 2010). "Microsoft Word – Gianvi Pharmacist Letter – RevD – Final 7-1-10 – web versi...". Archived from the original on March 14, 2012. https://web.archive.org/web/20120314145028/http://www.tevausa.com/assets/base/products/Gianvi_Letter_7-1-10.pdf. Retrieved December 26, 2010. 
  84. ↑ "Teva Pharmaceuticals USA, Inc. v. Sandoz, Inc.". http://www.scotusblog.com/case-files/cases/teva-pharmaceuticals-usa-inc-v-sandoz-inc/?wpmp_switcher=desktop. Retrieved January 27, 2015. 
  85. ↑ Thomas, Katie (2016-12-15). "20 States Accuse Generic Drug Companies of Price Fixing". The New York Times. https://www.nytimes.com/2016/12/15/business/generic-drug-price-lawsuit-teva-mylan.html. Retrieved 2016-12-16. 
  86. ↑ Mfg. by Watson Pharmaceuticals. See Actavis Acquisition and Watson Name Change, and Allergan, Inc. Acquisition and Actavis, plc Name Change
  87. ↑ DeNoon, D. (August 3, 2012). Generic singulair approved. Retrieved from http://www.webmd.com/asthma/news/20120803/generic-singulair-approved
  88. ↑ "Teva Announces Launch Of Generic Protonix Tablets". tevapharm.com. Archived from the original on December 29, 2007. https://web.archive.org/web/20071229041600/http://www.tevapharm.com/pr/2007/pr_708.asp. 

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