Chemistry:Icrucumab

From HandWiki
Short description: Monoclonal antibody
Icrucumab
Monoclonal antibody
TypeWhole antibody
SourceHuman
TargetVEGFR-1
Clinical data
Other namesIMC-18F1
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6514H10024N1756O2032S42
Molar mass146796.63 g·mol−1
 ☒N☑Y (what is this?)  (verify)

Icrucumab (IMC-18F1) is a human monoclonal antibody designed for the treatment of solid tumors.[1][2]

Icrucumab was developed by ImClone Systems Inc. It is undergoing Phase I trials.[3]

References

  1. "Statement On A Nonproprietary Name Adopted By The USAN Council: Icrucumab". American Medical Association. http://www.ama-assn.org/resources/doc/usan/icrucumab.pdf. 
  2. "Icrucumab, a fully human monoclonal antibody against the vascular endothelial growth factor receptor-1, in the treatment of patients with advanced solid malignancies: a Phase 1 study". Invest New Drugs 32 (2): 303–11. April 2014. doi:10.1007/s10637-013-9998-8. PMID 23903897. 
  3. Clinical trial number NCT00782002 for "Safety Study of IMC-18F1, to Treat Advanced Solid Tumors in Subjects That no Longer Respond to Standard Therapy" at ClinicalTrials.gov