Chemistry:Inositol nicotinate

Short description: Chemical compound

Inositol nicotinate

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	oral
ATC code	C04AC03 (WHO)
Legal status
Legal status	US: OTC
Identifiers
IUPAC name cyclohexane-1,2,3,4,5,6-hexayl hexanicotinate
CAS Number	6556-11-2
PubChem CID	3720
ChemSpider	16736141
UNII	A99MK953KZ
KEGG	D01813
Chemical and physical data
Formula	C42H30N6O12
Molar mass	810.732 g·mol−1
3D model (JSmol)	Interactive image
Melting point	255 °C (491 °F)
SMILES O=C(O[C@H]6[C@H](OC(=O)c1cccnc1)[C@H](OC(=O)c2cccnc2)[C@H](OC(=O)c3cccnc3)[C@@H](OC(=O)c4cccnc4)[C@@H]6OC(=O)c5cccnc5)c7cccnc7

Inositol nicotinate, also called inositol hexanicotinate and inositol hexaniacinate, is marketed in the United States as a "no-flush niacin" dietary supplement. Flushing, in physiology, essentially means that epidermal tissues have become reddened, such as when the skin is irritated from the histamine responses related to an allergic reaction, or from recent physical exercise, or even from anger or embarrassment.

This form of niacin is supposed to reduce or prevent flushing by being broken down into the metabolites niacin (nicotinic acid) and inositol at a slow rate.

See also

• Esterification
• Hydrolysis