Chemistry:New methylene blue
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3D model (JSmol)
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| Properties | |
| C18H22N3S:SCl ZnCl2 | |
| Molar mass | 484.22 g/mol |
| Melting point | 239 °C (462 °F; 512 K) |
| Boiling point | Decomposes |
| Hazards | |
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| GHS Signal word | WARNING |
| H302, H312, H332 | |
| P261, P264, P270, P271, P280, P301+317Script error: No such module "Preview warning".Category:GHS errors, P302+352, P304+340, P317Script error: No such module "Preview warning".Category:GHS errors, P321, P330, P362+364Script error: No such module "Preview warning".Category:GHS errors, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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New methylene blue (also NMB, and Basic Blue 24) is an organic compound of the thiazine class of heterocycles. It is used as a stain and as an antimicrobial agent. It is classified as an azine dye, and the chromophore is a cation, the anion is often unspecified.[1]
New Methylene Blue contains the word "New" in its name to differentiate the effectiveness of staining, between its predecessor methylene blue, the chemical structure of methylene blue, and the colors between the two.[2]
Applications
NMB is a staining agent used in diagnostic cytopathology and histopathology, typically for staining immature red blood cells. It is a supravital stain.[3] It is closely related to methylene blue, an older stain in wide use.
Safety
New methylene blue is toxic. Skin contact or inhalation should be avoided.
See also
- Methylene blue
- Brilliant Cresyl Blue
References
- ↑ Vennerstrom, Jonathan L.; Makler, Michael T.; Angerhofer, Cidy K.; Williams, Jean A. "Antimalarial dyes revisited: xanthenes, azines, oxazines, and thiazine" Antimicrobial Agents and Chemotherapy (1995), 39(12), 2671–7. doi:10.1128/AAC.39.12.2671.
- ↑ "New Methylene Blue as A Reticulocyte Stain". George Brecher. 1 Sep 1949. https://academic.oup.com/ajcp/article-abstract/19/9_ts/895/4828641.
- ↑ "Reticulocyte Count". Prentice-Hall. http://wps.prenhall.com/wps/media/objects/684/700987/ch07RET.pdf.
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