Chemistry:Ohmecarfentanil

Short description: Chemical compound

Ohmecarfentanil

Legal status
Legal status	CA: Schedule I DE: NpSG (Industrial and scientific use only) UK: Class A
Identifiers
IUPAC name Methyl 1-(2-hydroxy-2-phenylethyl)-3-methyl-4-(N-propanoylanilino)piperidine-4-carboxylate
PubChem CID	3R,4R: 10432482 3R,4S: 10071012
ChemSpider	3R,4R: 8607909 3R,4S: 8246552
Chemical and physical data
Formula	C25H32N2O4
Molar mass	424.541 g·mol−1
3D model (JSmol)	3R,4R: Interactive image 3R,4S: Interactive image
SMILES 3R,4R: CCC(=O)N(C1=CC=CC=C1)[C@@]2(CCN(C[C@H]2C)CC(C3=CC=CC=C3)O)C(=O)OC 3R,4S: CCC(=O)N(C1=CC=CC=C1)[C@]2(CCN(C[C@H]2C)CC(C3=CC=CC=C3)O)C(=O)OC
InChI 3R,4R: InChI=1S/C25H32N2O4/c1-4-23(29)27(21-13-9-6-10-14-21)25(24(30)31-3)15-16-26(17-19(25)2)18-22(28)20-11-7-5-8-12-20/h5-14,19,22,28H,4,15-18H2,1-3H3/t19-,22?,25-/m1/s1 Key:HVTQDIBOZUDMTH-PJHDFATGSA-N 3R,4S: InChI=1S/C25H32N2O4/c1-4-23(29)27(21-13-9-6-10-14-21)25(24(30)31-3)15-16-26(17-19(25)2)18-22(28)20-11-7-5-8-12-20/h5-14,19,22,28H,4,15-18H2,1-3H3/t19-,22?,25+/m1/s1 Key:HVTQDIBOZUDMTH-CGPDNSSVSA-N

Ohmecarfentanil (RTI-4614-38), also known as Ohlofentanil, is a mu opioid receptor agonist from the class of fentanyl analogues which was found to be 30,000 times more potent than morphine in the rhesus monkey single dose suppression test. This makes ohmecarfentanil, along with some closely related analogues, among the most potent opioid agonists known at this time, even surpassing lofentanil and ohmefentanyl.

See also

• Opioid potency comparison