Chemistry:Raphanin

From HandWiki
Raphanin
Raphanin.png
Names
Preferred IUPAC name
(1E)-4-Isothiocyanato-1-(methanesulfinyl)but-1-ene
Other names
Sulforaphen; Sulforaphene; Sativin
Identifiers
3D model (JSmol)
ChemSpider
UNII
Properties
C6H9NOS2
Molar mass 175.26 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Raphanin is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage.[1][2] It was first described in 1947.[3][4]

Basic research

In vitro, raphanin inhibits some fungi and various bacteria including Staphylococcus, Streptococcus, Pneumococcus and Escherichia coli.[3][5][6]

Minimum inhibitory concentration of raphanin[7]
Bacteria MIC (mg/mL)
Staphylococcus 0.04
Shigella dysenteriae 0.125
Salmonella typhi 0.125
Escherichia coli 0.2

See also

References

  1. Sinha, Nirmal K.; Hui, Y. H.; Muhammad Siddiq; Jasim Ahmed (2010). Handbook of Vegetables and Vegetable Processing. John Wiley and Sons. p. 156. ISBN 978-0-8138-1541-1. https://books.google.com/books?id=Fz58umYZVK8C&pg=PT156. 
  2. Michael Meyer; Sieghard T. Adam (2008). "Comparison of glucosinolate levels in commercial broccoli and red cabbage from conventional and ecological farming". European Food Research and Technology 226 (6): 1429–1437. doi:10.1007/s00217-007-0674-0. 
  3. 3.0 3.1 Baron, Abraham Louis (1950). Handbook of antibiotics. Reinhold. p. 215. ISBN 9780598986818. https://books.google.com/books?id=vtbQAAAAMAAJ. 
  4. Ivãnovics, G.; S. Horvãth (1947). "Raphanin, an Antibacterial Principle of the Radish (Raphanus sativus)". Nature 160 (4061): 297–298. doi:10.1038/160297a0. PMID 20261763. Bibcode1947Natur.160..297I. 
  5. Florey, Howard (1949). Antibiotics: a survey of penicillin, streptomycin, and other antimicrobial substances from fungi, actinomycetes, bacteria, and plants. Oxford University Press. pp. 625–6. https://books.google.com/books?id=iNXwAAAAMAAJ. 
  6. Ivànovics, G.; Horvath, S. (1947). "Isolation and Properties of Raphanin, an Antibacterial Substance from Radish Seed". Experimental Biology and Medicine 66 (3): 625–630. doi:10.3181/00379727-66-16177. PMID 18900045. 
  7. Chang, Hson-Mou; Pui-Hay, Paul; Yao, Sih-Cheng (2001). Pharmacology and Applications of Chinese Material Medical. World Scientific. p. 969. ISBN 978-981-02-3694-6. https://books.google.com/books?id=SU_ZX6lI1OIC&pg=PA969.