Chemistry:Sterubin
From HandWiki
| |
| Names | |
|---|---|
| IUPAC name
(2S)-3′,4′,5-Trihydroxy-7-methoxyflavan-4-one
| |
| Systematic IUPAC name
(2S)-2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-2,3-dihydro-4H-1-benzopyran-4-one | |
| Other names
7-Methoxy-3′,4′,5-trihydroxyflavanone
| |
| Identifiers | |
3D model (JSmol)
|
|
| ChemSpider | |
PubChem CID
|
|
| UNII | |
| |
| |
| Properties | |
| C16H14O6 | |
| Molar mass | 302.28 g/mol |
| Density | 1.458 g/mL |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
| |
| Infobox references | |
Tracking categories (test):
Sterubin (7-methoxy-3',4',5-trihydroxyflavanone) is a bitter-masking flavanone extracted from Yerba Santa (Eriodictyon californicum) a plant growing in America.[1]
Sterubin is one of the four flavanones identified by Symrise in this plant which elicit taste-modifying properties. The others are homoeriodictyol, its sodium salt, and eriodictyol.[2]
Recent research has demonstrated some neuroprotective properties of Sterubin in vitro, but more research is needed before it can be considered a true drug candidate.[3][4][5]
References
- ↑ Patricia Kaminski and Richard Katz. Yerba Santa Eriodictyon californicum. Flower Essence Society.
- ↑ "Evaluation of bitter masking flavanones from Herba Santa (Eriodictyon californicum (H. and A.) Torr., Hydrophyllaceae)". J. Agric. Food Chem. 53 (15): 6061–6. July 2005. doi:10.1021/jf0505170. PMID 16028996.
- ↑ Wolfgang Fischer; Antonio Currais; Zhibin Liang; Antonio Pinto; Pamela Maher (February 2019). "Old age-associated phenotypic screening for Alzheimer's disease drug candidates identifies sterubin as a potent neuroprotective compound from Yerba santa". Redox Biology 21: 101089. doi:10.1016/j.redox.2018.101089. PMID 30594901.
- ↑ Zhibin Liang; Pamela Maher (November 2022). "Structural Requirements for the Neuroprotective and Anti-Inflammatory Activities of the Flavanone Sterubin". Antioxidants 11 (11): 2197. doi:10.3390/antiox11112197. PMID 36358569.
- ↑ Batya Swift Yasgur. [1]. (Paywalled) Medscape. February 2019.
 |  |
