Medicine:Vegetation (pathology)

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Histopathology of a vegetation of bacterial endocarditis, taken from a valve repair, H&E stain.
Short description: Abnormal growths in the heart associated with endocarditis

In medicine, a vegetation is an abnormal growth[1] named for its similarity to natural vegetation. Vegetations are often associated with endocarditis.[2][3][4] They can be made of fibrin[5] and platelets.[6]

Types

Certain conditions are associated with specific vegetation patterns:

Condition Size Infective?
Infective endocarditis related to Staphylococcus aureus Generally large Yes
Rheumatic fever related to Streptococcus pyogenes Typically small
Libman–Sacks endocarditis related to systemic lupus erythematosus Small No (sterile)
Nonbacterial thrombotic endocarditis (NBTE) Small No (sterile)

References

  1. ↑ "Vegetation" at Dorland's Medical Dictionary
  2. ↑ "Three fatal cases of rapidly progressive infective endocarditis caused by Staphylococcus aureus: one case with huge vegetation". Circ. J. 71 (9): 1488–91. September 2007. doi:10.1253/circj.71.1488. PMID 17721034. 
  3. ↑ "Clinical and echocardiographic predictors of morbidity and mortality in infective endocarditis: the significance of vegetation size". Isr. Med. Assoc. J. 9 (5): 365–9. May 2007. PMID 17591374. 
  4. ↑ "eMedicine/Stedman Medical Dictionary Lookup!". http://www.emedicine.com/asp/dictionary.asp?exact=Y&keyword=vegetative+endocarditis. 
  5. ↑ "Pathology Education: Cardiovascular". http://www.pathology.vcu.edu/education/cardio/lab2.f.html. 
  6. ↑ "eMedicine/Stedman Medical Dictionary Lookup!". http://www.emedicine.com/asp/dictionary.asp?exact=Y&keyword=vegetation. 




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