Chemistry:Erucin
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| Names | |
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| IUPAC name
1-Isothiocyanato-4-methylsulfanylbutane
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| Other names
4-Methylthiobutyl isothiocyanate
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| Identifiers | |
3D model (JSmol)
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PubChem CID
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| Properties | |
| C6H11NS2 | |
| Molar mass | 161.28 g·mol−1 |
| Hazards | |
| GHS pictograms | 
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| GHS Signal word | Danger |
| H314 | |
| P260, P264, P264+265Script error: No such module "Preview warning".Category:GHS errors, P280, P301+330+331, P302+361+354Script error: No such module "Preview warning".Category:GHS errors, P304+340, P305+354+338Script error: No such module "Preview warning".Category:GHS errors, P316Script error: No such module "Preview warning".Category:GHS errors, P317Script error: No such module "Preview warning".Category:GHS errors, P321, P363, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Erucin (4-methylthiobutyl isothiocyanate) is a dietary isothiocyanate present in cruciferous vegetables that is considered a potential cancer chemopreventive nutraceutical.
Characteristics
Erucin is produced by the enzymatic hydrolysis of the glucosinolate glucoerucin present in Eruca sativa Mill. seeds (Brassicaceae or Cruciferae). Erucin has structural analogies with sulforaphane (SFN), an isothiocyanate derived from glucoraphanin, a glucosinolate present in some edible crucifers, and known in the literature for its chemopreventive properties. Different isothiocyanates exert anticancer properties on many tumor types (liver, breast, bladder, lung, and pancreatic), and in particular, SFN is employed in a pilot randomized controlled clinical trial in advanced pancreatic cancer.[2]
References
- ↑ "Erucin" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/78160#section=Safety-and-Hazards.
- ↑ Martelli, Alma (2019). "Anticancer Activities of Erucin a H2S-Donor Isothiocyanate From Eruca Sativa Mill.: Is H2S the Real Player?". Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders 327-328. doi:10.1016/B978-0-12-821038-3.00023-9.
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