Biology:Strombine dehydrogenase
From HandWiki
| strombine dehydrogenase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.5.1.22 | ||||||||
| CAS number | 79393-84-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a strombine dehydrogenase (EC 1.5.1.22) is an enzyme that catalyzes the chemical reaction
- N-(carboxymethyl)-D-alanine + NAD+ + H2O [math]\displaystyle{ \rightleftharpoons }[/math] glycine + pyruvate + NADH + H+
The 3 substrates of this enzyme are N-(carboxymethyl)-D-alanine, NAD+, and H2O, whereas its 4 products are glycine, pyruvate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming). Other names in common use include strombine[N-(carboxymethyl)-D-alanine]dehydrogenase, and N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase.
References
- "Strombine [N-(carboxymethyl)-D-alanine] dehydrogenase and alanopine [meso-N-(1-carboxyethyl)-alanine dehydrogenase from the mussel Mytilus edulis L". Biochem. Soc. Trans. 9: 297–298. 1981.
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