Biology:23S rRNA pseudouridine746 synthase
From HandWiki
Short description: Enzyme
| 23S rRNA pseudouridine746 synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.4.99.29 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
23S rRNA pseudouridine746 synthase (EC 5.4.99.29, RluA, 23S RNA PSI746 synthase, 23S rRNA pseudouridine synthase, pseudouridine synthase RluA) is an enzyme with systematic name 23S rRNA-uridine746 uracil mutase.[1][2][3] This enzyme catalyses the following chemical reaction
- 23S rRNA uridine746 [math]\displaystyle{ \rightleftharpoons }[/math] 23S rRNA pseudouridine746
RluA is the only protein responsible for the in vivo formation of 23S RNA pseudouridine746.
References
- ↑ "Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure". Molecular Cell 24 (4): 535–45. November 2006. doi:10.1016/j.molcel.2006.09.017. PMID 17188032.
- ↑ "Functional effect of deletion and mutation of the Escherichia coli ribosomal RNA and tRNA pseudouridine synthase RluA". The Journal of Biological Chemistry 274 (27): 18880–6. July 1999. doi:10.1074/jbc.274.27.18880. PMID 10383384.
- ↑ "A dual-specificity pseudouridine synthase: an Escherichia coli synthase purified and cloned on the basis of its specificity for psi 746 in 23S RNA is also specific for psi 32 in tRNA(phe)". RNA 1 (4): 437–48. June 1995. PMID 7493321.
External links
- 23S+rRNA+pseudouridine746+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
 |  |
