Biology:4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase
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Short description: Class of enzymes
| 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.2.34 | ||||||||
| CAS number | 86611-90-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase (EC 4.1.2.34) catalyzes the chemical reaction
- (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] 2-formylbenzoate + pyruvate
This enzyme participates in naphthalene and anthracene degradation.
Nomenclature
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase (pyruvate-forming). Other names in common use include 2'-carboxybenzalpyruvate aldolase, (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate, 2-carboxybenzaldehyde-lyase, and (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase.
References
- "Phthalate pathway of phenanthrene metabolism: formation of 2'-carboxybenzalpyruvate". Journal of Bacteriology 154 (1): 113–7. April 1983. PMID 6833175.
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