Biology:ACSS3

From HandWiki
Short description: Protein-coding gene in humans


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Acyl-CoA synthetase short-chain family member 3 is a protein that in humans is encoded by the ACSS3 gene.[1]

Function

ACSS3 is part of a family known as Acyl-coenzyme A synthetases (ACSs), which catalyze the initial reaction in fatty acid metabolism. This reaction activates fatty acids via thioesterification to CoA, thereby allowing their participation in both anabolic and catabolic pathways. The existence of many ACSs suggests that each plays a unique role, directing the acyl-CoA product to a specific metabolic fate. Knowing the full complement of ACS genes in the human genome will facilitate future studies to characterize their specific biological functions.[2]

References

  1. "Entrez Gene: Acyl-CoA synthetase short-chain family member 3". https://www.ncbi.nlm.nih.gov/gene/79611. 
  2. "Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome". Journal of Lipid Research 48 (12): 2736–50. Dec 2007. doi:10.1194/jlr.M700378-JLR200. PMID 17762044. 

Further reading