Biology:Alpha-bisabolene synthase
From HandWiki
| α-isabolene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.38 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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α-Bisabolene synthase (EC 4.2.3.38, bisabolene synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-α-bisabolene-forming).[1] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] (E)-α-bisabolene + diphosphate
This synthase requires a divalent cation cofactor (Mg2+ or, to a lesser extent, Mn2+) to neutralize the negative charge of the diphosphate leaving group.
References
- ↑ "Terpenoid-based defenses in conifers: cDNA cloning, characterization, and functional expression of wound-inducible (E)-alpha-bisabolene synthase from grand fir (Abies grandis)". Proceedings of the National Academy of Sciences of the United States of America 95 (12): 6756–61. June 1998. doi:10.1073/pnas.95.12.6756. PMID 9618485. Bibcode: 1998PNAS...95.6756B.
External links
- Alpha-bisabolene+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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