Biology:Alpha-guaiene synthase

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α-guaiene synthase
Identifiers
EC number4.2.3.87
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

α-Guaiene synthase (EC 4.2.3.87, PatTps177 (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, α-guaiene-forming).[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] α-guaiene + diphosphate

This enzyme requires Mg2+.

References

  1. "The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases". Archives of Biochemistry and Biophysics 454 (2): 123–36. October 2006. doi:10.1016/j.abb.2006.08.006. PMID 16970904. 
  2. "Characterization of δ-guaiene synthases from cultured cells of Aquilaria, responsible for the formation of the sesquiterpenes in agarwood". Plant Physiology 154 (4): 1998–2007. December 2010. doi:10.1104/pp.110.161828. PMID 20959422. 

External links