Biology:Alpha-seco-amyrin synthase

From HandWiki
α-seco-amyrin synthase
Identifiers
EC number5.4.99.52
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

α-seco-amyrin synthase (EC 5.4.99.52) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, alpha-seco-amyrin-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene [math]\displaystyle{ \rightleftharpoons }[/math] alpha-seco-amyrin

The enzyme from Arabidopsis thaliana is multifunctional.

References

  1. "Origin of structural diversity in natural triterpenes: direct synthesis of seco-triterpene skeletons by oxidosqualene cyclase". Journal of the American Chemical Society 129 (5): 1450–5. February 2007. doi:10.1021/ja066873w. PMID 17263431. 

External links