Biology:Biochanin-A reductase

From HandWiki
Short description: Class of enzymes
biochanin-A reductase
Identifiers
EC number1.3.1.46
CAS number112198-90-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a biochanin-A reductase (EC 1.3.1.46) is an enzyme that catalyzes the chemical reaction

dihydrobiochanin A + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] biochanin A + NADPH + H+

Thus, the two substrates of this enzyme are dihydrobiochanin A and NADP+, whereas its 3 products are biochanin A, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is dihydrobiochanin-A:NADP+ Delta2-oxidoreductase. This enzyme participates in isoflavonoid biosynthesis.

References

  • "Isolation of NADPH:isoflavone oxidoreductase, a new enzyme of pterocarpan biosynthesis in cell suspensions of Cicer arietinum". FEBS Lett. 213 (2): 324–328. 1987. doi:10.1016/0014-5793(87)81515-6.