Biology:Carboxypeptidase U
From HandWiki
| Carboxypeptidase U | |||||||||
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| Identifiers | |||||||||
| EC number | 3.4.17.20 | ||||||||
| CAS number | 156621-18-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Carboxypeptidase U (EC 3.4.17.20, arginine carboxypeptidase, carboxypeptidase R, plasma carboxypeptidase B, thrombin-activatable fibrinolysis inhibitor) is an enzyme.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
Pro-carboxypeptidase U in (human) plasma is activated by thrombin or plasmin during clotting to form the unstable carboxypeptidase U.
See also
References
- ↑ "Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma". The Journal of Biological Chemistry 266 (32): 21833–8. November 1991. PMID 1939207.
- ↑ "Pro-carboxypeptidase R cleaves bradykinin following activation". International Archives of Allergy and Immunology 103 (4): 400–4. 1994. doi:10.1159/000236661. PMID 8130654.
- ↑ "Carboxypeptidase U, a plasma carboxypeptidase with high affinity for plasminogen". The Journal of Biological Chemistry 269 (22): 15937–44. June 1994. PMID 8195249.
- ↑ "Activation and characterization of procarboxypeptidase B from human plasma". Biochemistry 34 (17): 5811–6. May 1995. doi:10.1021/bi00017a012. PMID 7727441.
- ↑ "Coagulation-dependent inhibition of fibrinolysis: role of carboxypeptidase-U and the premature lysis of clots from hemophilic plasma". Blood 88 (10): 3815–23. November 1996. PMID 8916945.
External links
- Carboxypeptidase+U at the US National Library of Medicine Medical Subject Headings (MeSH)
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