Biology:DNPEP
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Aspartyl aminopeptidase is an enzyme that in humans is encoded by the DNPEP gene.[1][2]
Function
The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in the general metabolism of intracellular proteins.[2]
See also
References
- ↑ "Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase". The Journal of Biological Chemistry 273 (26): 15961–70. Jun 1998. doi:10.1074/jbc.273.26.15961. PMID 9632644.
- ↑ 2.0 2.1 "Entrez Gene: DNPEP aspartyl aminopeptidase". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23549.
Further reading
- "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology 3 (1): 89. 2007. doi:10.1038/msb4100134. PMID 17353931.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. Oct 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "Angiotensinase activities in the kidney of renovascular hypertensive rats". Peptides 24 (5): 755–60. May 2003. doi:10.1016/S0196-9781(03)00121-9. PMID 12895663.
- "Identification of histidine residues important in the catalysis and structure of aspartyl aminopeptidase". Archives of Biochemistry and Biophysics 407 (2): 176–83. Nov 2002. doi:10.1016/S0003-9861(02)00494-0. PMID 12413488.
External links
- The MEROPS online database for peptidases and their inhibitors: M18.002
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Aspartyl aminopeptidase (DNPEP)
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