Biology:Carotenoid isomerooxygenase

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Carotenoid isomerooxygenase
Identifiers
EC number1.13.11.65
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Carotenoid isomerooxygenase (EC 1.13.11.65, ninaB (gene)) is an enzyme with systematic name zeaxanthin:oxygen 15,15'-oxidoreductase (bond-cleaving, cis-isomerizing).[1] This enzyme catalyses the following chemical reaction

zeaxanthin + O2 [math]\displaystyle{ \rightleftharpoons }[/math] (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal

The enzyme from the moth Galleria mellonella and the fruit fly Drosophila melanogaster takes part in the synthesis of retinal .

References

  1. "NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide". Proceedings of the National Academy of Sciences of the United States of America 105 (48): 19000–5. December 2008. doi:10.1073/pnas.0807805105. PMID 19020100. Bibcode2008PNAS..10519000O. 

External links