Biology:Cis-abienol synthase

From HandWiki
Short description: Enzyme
cis-abienol synthase
Identifiers
EC number4.2.3.140
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

cis-Abienol synthase (EC 4.2.3.140, Z-abienol synthase, CAS, ABS) is an enzyme with systematic name (13E)-8α-hydroxylabd-13-en-15-yl-diphosphate-lyase (cis-abienol forming).[1][2] This enzyme catalyses the following chemical reaction

(13E)-8α-hydroxylabd-13-en-15-yl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] cis-abienol + diphosphate

This enzyme is isolated from the plants Abies balsamea (balsam fir) and Nicotiana tabacum (tobacco).

References

  1. "Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production". The Journal of Biological Chemistry 287 (15): 12121–31. April 2012. doi:10.1074/jbc.m111.317669. PMID 22337889. 
  2. "Characterization of two genes for the biosynthesis of the labdane diterpene Z-abienol in tobacco (Nicotiana tabacum) glandular trichomes". The Plant Journal 72 (1): 1–17. October 2012. doi:10.1111/j.1365-313x.2012.05068.x. PMID 22672125. 

External links