Biology:Cycloeucalenol cycloisomerase
From HandWiki
| cycloeucalenol cycloisomerase | |||||||||
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| Identifiers | |||||||||
| EC number | 5.5.1.9 | ||||||||
| CAS number | 60496-19-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a cycloeucalenol cycloisomerase (EC 5.5.1.9) is an enzyme that catalyzes the chemical reaction
- cycloeucalenol [math]\displaystyle{ \rightleftharpoons }[/math] obtusifoliol
Hence, this enzyme has one substrate, cycloeucalenol, and one product, obtusifoliol.
This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. The systematic name of this enzyme class is cycloeucalenol lyase (cyclopropane-decyclizing). This enzyme is also called cycloeucalenol---obtusifoliol isomerase. This enzyme participates in biosynthesis of steroids.
References
- "Plant sterol metabolism. Enzymatic cleavage of the 9beta, 19beta-cyclopropane ring of cyclopropyl sterols in bramble tissue cultures". J. Biol. Chem. 249 (13): 4267–74. 1974. PMID 4369016.
- "7-oxo-24ξ(28)-dihydrocycloeucalenol, a potent inhibitor of plant sterol biosynthesis". Phytochemistry 21 (8): 1969–1974. 1982. doi:10.1016/0031-9422(82)83024-0.
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