Biology:Lycopene beta-cyclase
From HandWiki
| Lycopene β-cyclase | |||||||||
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| Identifiers | |||||||||
| EC number | 5.5.1.19 | ||||||||
| CAS number | 220801-82-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Lycopene β-cyclase (EC 5.5.1.19, CrtL, CrtL-b, CrtY) is an enzyme with systematic name carotenoid beta-end group lyase (decyclizing).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- carotenoid ψ-end group [math]\displaystyle{ \rightleftharpoons }[/math] carotenoid β-end group
This enzyme requires NAD(P)H. It converts Lycopene (2 ψ ends) into β-carotene (2 β ends).
References
- ↑ "Cloning and functional expression in Escherichia coli of a cyanobacterial gene for lycopene cyclase, the enzyme that catalyzes the biosynthesis of beta-carotene". FEBS Letters 328 (1–2): 130–8. August 1993. doi:10.1016/0014-5793(93)80980-9. PMID 8344419.
- ↑ "Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp strain PCC7942". The Plant Cell 6 (8): 1107–21. August 1994. doi:10.1105/tpc.6.8.1107. PMID 7919981.
- ↑ "Metabolism of cyclic carotenoids: a model for the alteration of this biosynthetic pathway in Capsicum annuum chromoplasts". The Plant Journal 8 (3): 417–24. September 1995. doi:10.1046/j.1365-313x.1995.08030417.x. PMID 7550379.
- ↑ "Cloning and characterization of the cDNA for lycopene beta-cyclase from tomato reveals decrease in its expression during fruit ripening". Plant Molecular Biology 30 (4): 807–19. February 1996. doi:10.1007/bf00019013. PMID 8624411.
- ↑ "Involvement of NADPH in the cyclization reaction of carotenoid biosynthesis". FEBS Letters 515 (1–3): 133–6. March 2002. doi:10.1016/s0014-5793(02)02453-5. PMID 11943208.
- ↑ "Identification of a fourth family of lycopene cyclases in photosynthetic bacteria". Proceedings of the National Academy of Sciences of the United States of America 104 (28): 11784–9. July 2007. doi:10.1073/pnas.0702984104. PMID 17606904.
External links
- Lycopene+beta-cyclase at the US National Library of Medicine Medical Subject Headings (MeSH)
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