Biology:Terpentedienyl-diphosphate synthase
From HandWiki
Short description: Type of enzyme
| Terpentedienyl-diphosphate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.5.1.15 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Terpentedienyl-diphosphate synthase (EC 5.5.1.15, terpentedienol diphosphate synthase, Cyc1, clerodadienyl diphosphate synthase) is an enzyme with systematic name terpentedienyl-diphosphate lyase (decyclizing).[1][2][3] This enzyme catalyses the following chemical reaction
- geranylgeranyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] terpentedienyl diphosphate
This enzyme requires Mg2+.
References
- ↑ "Eubacterial diterpene cyclase genes essential for production of the isoprenoid antibiotic terpentecin". Journal of Bacteriology 183 (20): 6085–94. October 2001. doi:10.1128/jb.183.20.6085-6094.2001. PMID 11567009.
- ↑ "Functional analysis of eubacterial diterpene cyclases responsible for biosynthesis of a diterpene antibiotic, terpentecin". The Journal of Biological Chemistry 277 (40): 37098–104. October 2002. doi:10.1074/jbc.m206382200. PMID 12138123.
- ↑ "A new approach for the investigation of isoprenoid biosynthesis featuring pathway switching, deuterium hyperlabeling, and 1H NMR spectroscopy. The reaction mechanism of a novel streptomyces diterpene cyclase". The Journal of Organic Chemistry 68 (14): 5433–8. July 2003. doi:10.1021/jo026728a. PMID 12839434.
External links
- Terpentedienyl-diphosphate+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
 |  |
