Biology:D-glutamate cyclase

From HandWiki
D-glutamate cyclase
Identifiers
EC number4.2.1.48
CAS number37290-80-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme D-glutamate cyclase (EC 4.2.1.48) catalyzes the chemical reaction

D-glutamate [math]\displaystyle{ \rightleftharpoons }[/math] 5-oxo-Dproline + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming). This enzyme is also called D-glutamate hydro-lyase (cyclizing). This enzyme participates in D-glutamine and D-glutamate metabolism.

References

  • "THE OPTICALLY-SPECIFIC ENZYMATIC CYCLIZATION OF D-GLUTAMATE". Biochem. Z. 338: 217–29. 1963. PMID 14087295.