Biology:Flavin prenyltransferase
From HandWiki
| flavin prenyltransferase | |||||||||
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 Flavin prenyltransferase homododekamer, Pseudomonas aeruginosa | |||||||||
| Identifiers | |||||||||
| EC number | 2.5.1.129 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Flavin prenyltransferase EC 2.5.1.129 UbiX, that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN)[1] for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
Catalytic activity:
- Dimethylallyl phosphate + FMNH2 [math]\displaystyle{ \rightleftharpoons }[/math] prenylated FMNH2 + phosphate.
References
- ↑ "UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis". Nature 522 (7557): 502–6. June 2015. doi:10.1038/nature14559. PMID 26083743.
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