Biology:Fusicocca-2,10(14)-diene synthase

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Fusicocca-2,10(14)-diene synthase
Identifiers
EC number4.2.3.43
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Fusicocca-2,10(14)-diene synthase (EC 4.2.3.43, fusicoccadiene synthase, PaFS, PaDC4) is an enzyme with systematic name geranylgeranyl diphosphate-lyase (fusicocca-2,10(14)-diene-forming).[1] This enzyme catalyses the following chemical reaction

geranylgeranyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] fusicocca-2,10(14)-diene + diphosphate

This multifunctional enzyme also has EC 2.5.1.29, farnesyltranstransferase, activity.

References

  1. "Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi". Proceedings of the National Academy of Sciences of the United States of America 104 (9): 3084–8. February 2007. doi:10.1073/pnas.0608426104. PMID 17360612. 

External links