Biology:Influenza A virus subtype H1N2
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Virus classification 
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| Influenza (Flu) |
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Influenza A virus subtype H1N2 (A/H1N2) is a subtype of the species Influenza A virus (sometimes called bird flu virus). It is currently endemic in pig populations and is occasionally seen in humans.
The virus does not cause more severe illness than other influenza viruses, and no unusual increases in influenza activity have been associated with it.
History
Between December 1988 and March 1989, 19 influenza H1N2 virus isolates were identified in 6 cities in China , but the virus did not spread further.[1]
A(H1N2) was identified during the 2001–02 flu season (northern hemisphere) in Canada, the U.S., Ireland, Latvia, France, Romania, Oman, India, Malaysia, and Singapore with earliest documented outbreak of the virus occurring in India on May 31, 2001.
On February 6, 2002, the World Health Organization (WHO) in Geneva and the Public Health Laboratory Service (PHLS) in the United Kingdom reported the identification influenza A(H1N2) virus from humans in the UK, Israel, and Egypt.
The 2001–02 Influenza A(H1N2) Wisconsin strain appears to have resulted from the reassortment of the genes of the currently circulating influenza A(H1N1) and A(H3N2) subtypes.
In March 2018 a single case of H1N2 was identified in a 19-month old in the Netherlands. [2]
In January 2019 a single case of H1N2 was identified in Sweden. [3]
Because the hemagglutinin protein of the virus is similar to that of the currently[when?] circulating A(H1N1) viruses and the neuraminidase protein is similar to that of the current A(H3N2) viruses, the seasonal flu vaccine should provide good protection against influenza virus as well as protection against the currently circulating seasonal A(H1N1), A(H3N2), and B viruses.
In October 2020, a case of the H1N2 variant H1N2v was confirmed in Alberta, Canada and was the first confirmed human case in the country.[4]
References
This article incorporates public domain material from the Centers for Disease Control and Prevention document "Questions and Answers About Influenza A(H1N2) Viruses".- This article incorporates public domain material from the Centers for Disease Control and Prevention document "2001-02 INFLUENZA SEASON SUMMARY".
- ↑ Guo, YJ; Xu, XY; Cox, NJ (1992). "Human influenza A (H1N2) viruses isolated from China". The Journal of General Virology 73 (2): 383–7. doi:10.1099/0022-1317-73-2-383. PMID 1538194.
- ↑ Meijer A, Swaan CM, Voerknecht M, Jusic E, van den Brink S, Wijsman LA (2018). "Case of seasonal reassortant A(H1N2) influenza virus infection, the Netherlands, March 2018.". Euro Surveill 23 (15). doi:10.2807/1560-7917.ES.2018.23.15.18-00160. PMID 29667576. PMC 6836195. https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29667576.
- ↑ Wiman Å, Enkirch T, Carnahan A, Böttiger B, Hagey TS, Hagstam P (2019). "Novel influenza A(H1N2) seasonal reassortant identified in a patient sample, Sweden, January 2019.". Euro Surveill 24 (9). doi:10.2807/1560-7917.ES.2019.24.9.1900124. PMID 30862332. PMC 6402178. https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30862332.
- ↑ "Alberta confirms first Canadian case of H1N2 flu virus in a human". CalgaryHerald. 2020-11-04. https://calgaryherald.com/news/local-news/alberta-confirms-rare-variant-of-h1n2-flu-virus.
- "Phylogenetic analysis of H1N2 isolates of influenza A virus from pigs in the United States". Virus Res. 87 (2): 173–9. August 2002. doi:10.1016/S0168-1702(02)00053-9. PMID 12191781.
- CDC (2017-04-13). "Information on Avian Influenza". https://www.cdc.gov/flu/avian/gen-info/facts.htm.
External links
- Influenza Research Database Database of influenza genomic sequences and related information.
Wikidata ☰ Q3111968 entry
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