Biology:Isonocardicin synthase
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Short description: Class of enzymes
| isonocardicin synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.38 | ||||||||
| CAS number | 118246-74-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an isonocardicin synthase (EC 2.5.1.38) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + nocardicin E [math]\displaystyle{ \rightleftharpoons }[/math] 5'-methylthioadenosine + isonocardicin A
Thus, the two substrates of this enzyme are S-adenosyl-L-methionine and nocardicin E, whereas its two products are 5'-methylthioadenosine and isonocardicin A.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase. This enzyme is also called nocardicin aminocarboxypropyltransferase.
References
- "Cell-free biosynthesis of nocardicin A from nocardicin E and S-adenosylmethionine". J. Am. Chem. Soc. 110 (24): 8238–8239. 1988. doi:10.1021/ja00232a047.
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