The first sequences of keratins revealed that keratins could be grouped into two categories based on their sequence homologies.[1][2] These two groups of keratins were named as type I and type II keratins.[2] These two categories also represent the first two categories of the superfamily of intermediate filament proteins.
Keratins in this table are classified in the first two columns according to the nomenclature established in 2006.[3] Other names previously used are listed in columns 3 and 4.
Type I keratins
Human epithelial keratins
| Protein name[3] |
Gene name[3] |
Other protein name |
Other gene name
|
| K9 |
KRT9 |
Ka9 |
|
| K10 |
KRT10 |
Ka10 |
|
| K12 |
KRT12 |
Ka12 |
|
| K13 |
KRT13 |
Ka13 |
|
| K14 |
KRT14 |
Ka14 |
|
| K15 |
KRT15 |
Ka15 |
|
| K16 |
KRT16 |
Ka16 |
|
| K17 |
KRT17 |
Ka17 |
|
| K18 |
KRT18 |
Ka18 |
|
| K19 |
KRT19 |
Ka19 |
|
| K20 |
KRT20 |
Ka20 |
|
| K23 |
KRT23 |
Ka23 |
|
| K24 |
KRT24 |
Ka24 |
|
| K25 |
KRT25 |
Ka38, K25irs1, K10C, hIRSa1 |
KRT25A
|
| K26 |
KRT26 |
Ka39, K25irs2, K10D |
|
| K27 |
KRT27 |
Ka40, K25irs3, K10B, hIRSa3.1 |
|
| K28 |
KRT28 |
Ka41, K25irs4, hIRSa2 |
|
Human hair keratins
| Protein name[3] |
Gene name[3] |
Other protein name |
Other gene name
|
| K31 |
KRT31 |
Ka25, Ha1 |
KRTHA1
|
| K32 |
KRT32 |
Ka26, Ha2 |
KRTHA2
|
| K33a |
KRT33A |
Ka27, Ha3-I |
KRTHA3A
|
| K33b |
KRT33B |
Ka28, Ha3-II |
KRTHA3B
|
| K34 |
KRT34 |
Ka29, Ha4 |
KRTHA4
|
| K35 |
KRT35 |
Ka30, Ha5 |
KRTHA5
|
| K36 |
KRT36 |
Ka31, Ha6 |
KRTHA6
|
| K37 |
KRT37 |
Ka32, Ha7 |
KRTHA7
|
| K38 |
KRT38 |
Ka33, Ha8 |
KRTHA8
|
| K39 |
KRT39 |
Ka35 |
|
| K40 |
KRT40 |
Ka36 |
|
Nonhuman hair/epithelial keratins
| Protein name[3] |
Gene name[3] |
Other protein name |
Other gene name
|
| K41 chimp, gorilla, dog[4] |
KRT41 chimp, gorilla, dog; KRT41P man, horse |
|
φhHaA, Ka34P man
|
| K42 mouse, rat |
KRT42 mouse, rat; KRT42P man |
Ka22 mouse, rat, K17n mouse, rat |
|
Human keratin pseudogenes
| Protein name[3] |
Gene name[3] |
Other protein name |
Other gene name
|
|
KRT221P |
|
φhHaB
|
|
KRT222P |
|
φKRTI, Ka21P
|
|
KRT223P |
|
φKRTJ, Ka37P
|
Type II keratins
Human epithelial keratin
| Protein name[3] |
Gene name[3] |
Other protein name |
Other gene name
|
| K1 |
KRT1 |
Kb1 |
|
| K2 |
KRT2 |
Kb2, K2e |
KRT2A
|
| K3 |
KRT3 |
Kb3 |
|
| K4 |
KRT4 |
Kb4 |
|
| K5 |
KRT5 |
Kb5 |
|
| K6a |
KRT6A |
Kb6 |
|
| K6b |
KRT6B |
Kb10 |
|
| K7 |
KRT7 |
Kb7 |
|
| K8 |
KRT8 |
Kb8 |
|
| K71 |
KRT71 |
Kb34, K6irs1 |
|
| K72 |
KRT72 |
Kb35, K6irs2 |
|
| K73 |
KRT73 |
Kb36, K6irs3 |
|
| K74 |
KRT74 |
Kb37, K6irs4 |
|
| K75 |
KRT75 |
Kb18, K6hf |
|
| K76 |
KRT76 |
Kb9, K2p |
KRT2B
|
| K77 |
KRT77 |
Kb39, K1b |
|
| K78 |
KRT78 |
Kb40, K5b |
|
| K79 |
KRT79 |
Kb38, K6I |
|
| K80 |
KRT80 |
Kb20 |
|
Human hair keratins
| Protein name[3] |
Gene name[3] |
Other protein name |
Other gene name
|
| K81 |
KRT81 |
Kb21, Hb1, K2.9 |
KRTHB1
|
| K82 |
KRT82 |
Kb22, Hb2 |
KRTHB2
|
| K83 |
KRT83 |
Kb23, Hb3, K2.10 |
KRTHB3
|
| K84 |
KRT84 |
Kb24, Hb4 |
KRTHB4
|
| K85 |
KRT85 |
Kb25, Hb5, K2.12 |
KRTHB5
|
| K86 |
KRT86 |
Kb26, Hb6, K2.11 |
KRTHB6
|
Human keratin pseudogenes
| Protein name[3] |
Gene name[3] |
Other protein name |
Other gene name
|
|
KRT121P |
|
φhHbD, Kb31P
|
|
KRT122P |
|
φhHbC, Kb30P
|
|
KRT123P |
|
φhHbB, Kb29P
|
|
KRT124P |
|
φhHbA, Kb28P
|
|
KRT125P |
|
φKRTH
|
|
KRT126P |
|
φKRTG, Kb19P
|
|
KRT127P |
|
φKRTF
|
|
KRT128P |
|
φKRTE
|
See also
References
- ↑ Hanukoglu, I.; Fuchs, E. (Nov 1982). "The cDNA sequence of a human epidermal keratin: divergence of sequence but conservation of structure among intermediate filament proteins.". Cell 31 (1): 243–52. doi:10.1016/0092-8674(82)90424-X. PMID 6186381. https://zenodo.org/record/890743.
- ↑ 2.0 2.1 Hanukoglu, I.; Fuchs, E. (Jul 1983). "The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins.". Cell 33 (3): 915–24. doi:10.1016/0092-8674(83)90034-X. PMID 6191871. https://zenodo.org/record/890739.
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. July 2006. doi:10.1083/jcb.200603161. PMID 16831889.
- ↑ Balmer, P; Bauer, A; Pujar, S; McGarvey, KM; Welle, M; Galichet, A; Müller, EJ; Pruitt, KD et al. (2017). "A curated catalog of canine and equine keratin genes.". PLOS ONE 12 (8): e0180359. doi:10.1371/journal.pone.0180359. PMID 28846680. Bibcode: 2017PLoSO..1280359B.
 | Original source: https://en.wikipedia.org/wiki/List of keratins. Read more |
