Biology:List of restriction enzyme cutting sites: A

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Main pages: Biology:List of restriction enzyme cutting sites and Biology:Restriction enzyme
Legend of nucleobases
Code Nucleotide represented
A Adenine (A)
C Cytosine (C)
G Guanine (G)
T Thymine (T)
N A, C, G or T
M A or C
R A or G
W A or T
Y C or T
S C or G
K G or T
H A, C or T
B C, G or T
V A, C or G
D A, G or T

This article contains a list of restriction enzymes whose names start with A and have a clearly defined cutting site.

The following information is given for each enzyme:

  • Name of Restriction Enzyme: Accepted name of the molecule, according to the internationally adopted nomenclature,[1][2] and bibliographical references. Note: When alphabetizing, enzymes are first ordered alphabetically by the acronyms (everything before the roman numeral); then enzymes of a given acronym are ordered alphabetically by the roman numeral, treating the numeral as a number and not a string of letters. This helps keep the entries ordered hierarchically while also alphabetic.(Further reading: see the section "Nomenclature" in the article "Restriction enzyme".)
  • PDB code: Code used to identify the structure of a protein in the PDB database of protein structures. The 3D atomic structure of a protein provides highly valuable information to understand the intimate details of its mechanism of action.[3][4]
  • REBASE Number: Number used to identify restriction enzymes in the REBASE restriction enzyme database. This database includes important information about the enzyme such as Recognition sequence, source, and Isoschizomers, as well as other data, such as the commercial suppliers of the enzyme.
  • Source: Organism that naturally produces the enzyme.
  • Recognition sequence: Sequence of DNA recognized by the enzyme and to which it specifically binds.
  • Cut: Displays the cut site and pattern and products of the cut. The recognition sequence and the cut site usually match, but sometimes the cut site can be dozens of nucleotides away from the recognition site.[5][6]
  • Isoschizomers and neoschizomers: An isoschizomer is a restriction enzyme that recognizes the same sequence as another. A neoschizomer is a special type of isoschizomer that recognizes the same sequence as another, but cuts in a different manner. A maximum number of 8–10 most common isoschizomers are indicated for every enzyme but there may be many more. Neoschizomers are shown in bold and green color font (e.g.: BamHI). When "None as of [date]" is indicated, that means that there were no registered isoschizomers in the databases on that date with a clearly defined cutting site. Isoschizomers indicated in white font and grey background correspond to enzymes not listed in the current lists, as in this not listed enzyme:  Abc123I 

Whole list navigation

Restriction enzymes

A

Enzyme PDB code REBASE Number Source Recognition sequence Cut Isoschizomers
AaaI 1 Acetobacter aceti 5' CGGCCG
3' GCCGGC 		5' ---C   GGCCG--- 3'
3' ---GCCGG   C--- 5' 		BseX3I, BstZI, EagI, EclXI, Eco52I, SenPT16I, XmaIII
AagI 4 Achromobacter agile 5' ATCGAT
3' TAGCTA 		5' ---AT   CGAT--- 3'
3' ---TAGC   TA--- 5' 		BanIII, BavCI, Bsa29I, BseCI, BspDI, Bsu15I, BsuTUI, ClaI
AanI 15358 Arthrobacter aurescens RFL2 5' TTATAA
3' AATATT 		5' ---TTA   TAA--- 3'
3' ---AAT   ATT--- 5' 		PsiI, Csp1BORF7380P
AarI[7] 2892 Arthrobacter aurescens SS2-322 5' CACCTGC
3' GTGGACG 		5' ---CACCTGCN3N   NNNN--- 3'
3' ---GTGGACGN3NNNNN   --- 5' 		PaqCI
AasI 5465 Arthrobacter aurescens RFL3 5' GACN6GTC
3' CTGN6CAG 		5' ---GACNNNN   NNGTC--- 3'
3' ---CTGNN   NNNNCAG--- 5' 		DrdI, DseDI
AatI[8] 6 Acetobacter aceti 5' AGGCCT
3' TCCGGA 		5' ---AGG   CCT--- 3'
3' ---TCC   GGA--- 5' 		AspMI, Eco147I,  Eco1524I,  PceI, Pme55I, SarI, Sru30DI, SteI
AatII[8][9][10][11] 7 Acetobacter aceti 5' GACGTC
3' CTGCAG 		5' ---GACGT   C--- 3'
3' ---C   TGCAG--- 5' 		Ssp5230I, ZraI
AauI 3010 Arthrobacter aurescens 5' TGTACA
3' ACATGT 		5' ---T   GTACA--- 3'
3' ---ACATG   T--- 5' 		 BsmRI,  Bsp1407I, BsrGI, BstAUI, Ssp4800I, SspBI
AbaI 3029 Azospirillum brasilense UQ 1796 5' TGATCA
3' ACTAGT 		5' ---T   GATCA--- 3'
3' ---ACTAG   T--- 5' 		BclI, BsiQI, BspXII, BstT7I, FbaI, Ksp22I,  ParI 
AbeI 3097 Azotobacter beijerinckii Slo 54-028 5' CCTCAGC
3' GGAGTCG 		5' ---CC   TCAGC--- 3'
3' ---GGAGT   CG--- 5' 		BbvCI
AbrI 8 Azospirillum brasilense 5' CTCGAG
3' GAGCTC 		5' ---C   TCGAG--- 3'
3' ---GAGCT   C--- 5' 		BluI, BspAAI, BssHI, EscI, PaeR7I, SciI, Sfr274I, Sol10179I, StrI, TliI
AbsI 14594 Arthrobacter sp. 7M06 5' CCTCGAGG
3' GGAGCTCC 		5' ---CC   TCGAGG--- 3'
3' ---GGAGCT   CC--- 5' 		None as of 4 Apr. 2019
AccI[12][13][14][15] 18 Acinetobacter calcoaceticus 5' GTMKAC
3' CAKMTG 		5' ---GT   MKAC--- 3'
3' ---CAKM   TG--- 5' 		FblI, XmiI
AccII[12][16] 19 Acinetobacter calcoaceticus 5' CGCG
3' GCGC 		5' ---CG   CG--- 3'
3' ---GC   GC--- 5' 		Bsh1236I, Bsp50I, BstFNI, BstUI, MvnI, SelI, BceBI, BepI, Bpu95I
AccIII[17] 20 Acinetobacter calcoaceticus 5' TCCGGA
3' AGGCCT 		5' ---T   CCGGA--- 3'
3' ---AGGCC   T--- 5' 		Aor13HI, BbvAIII, BlfI, BseAI, BsiMI, BspEI, CauB3I, Kpn2I, MroI, PtaI
Acc16I 2638 Acinetobacter calcoaceticus 16 5' TGCGCA
3' ACGCGT 		5' ---TGC   GCA--- 3'
3' ---ACG   CGT--- 5' 		AosI, AviII, FdiII, FspI, MstI, NsbI, PamI, Pun14627I
Acc36I[18] 4162 Acinetobacter calcoaceticus 36 5' ACCTGC
3' TGGACG 		5' ---ACCTGCN3N   NNNN--- 3'
3' ---TGGACGN3NNNNN   --- 5' 		BfuAI, BspMI, BveI
Acc65I[19] 14 Acinetobacter calcoaceticus 65 5' GGTACC
3' CCATGG 		5' ---G   GTACC--- 3'
3' ---CCATG   G--- 5' 		AhaB8I, Asp718I, KpnI, SthI
Acc113I 2665 Acinetobacter calcoaceticus 113 5' AGTACT
3' TCATGA 		5' ---AGT   ACT--- 3'
3' ---TCA   TGA--- 5' 		AssI,  BmcAI, Bpa34I,  DpaI, Eco255I, RflFII, ScaI, ZrmI
AccB1I 15 Acinetobacter calcoaceticus B1 5' GGYRCC
3' CCRYGG 		5' ---G   GYRCC--- 3'
3' ---CCRYG   G--- 5' 		BanI, BbvBI, BshNI, BspT107I, Eco64I, HgiCI, HgiHI, MspB4I
AccB2I 2666 Acinetobacter calcoaceticus B2 5' RGCGCY
3' YCGCGR 		5' ---RGCGC   Y--- 3'
3' ---Y   CGCGR--- 5' 		 BfoI,  Bme142I, Bsp143II, BstH2I, HaeII, LpnI
AccB7I[20] 16 Acinetobacter calcoaceticus B7 5' CCAN5TGG
3' GGTN5ACC 		5' ---CCANNNN   NTGG--- 3'
3' ---GGTN   NNNNACC--- 5' 		AcpII, Asp10HII, BasI, Esp1396I, PflBI, PflMI, Van91I
AccBSI[21] 2733 Acinetobacter calcoaceticus BS 5' CCGCTC
3' GGCGAG 		5' ---CCG   CTC--- 3'
3' ---GGC   GAG--- 5' 		BsrBI, BstD102I, Bst31NI, MbiI
AccEBI 17 Acinetobacter calcoaceticus EBF 65/65 5' GGATCC
3' CCTAGG 		5' ---G   GATCC--- 3'
3' ---CCTAG   G--- 5' 		AsiI, BamHI, Bce751I, Bsp98I, BspAAIII, CelI, OkrAI, Uba4009I
AceI 2571 Anabaena cedrorum 5' GCWGC
3' CGWCG 		5' ---G   CWGC--- 3'
3' ---CGWC   G--- 5' 		ApeKI, SuiI, Taq52I, TseI
AceII 2570 Anabaena cedrorum 5' GCTAGC
3' CGATCG 		5' ---GCTAG   C--- 3'
3' ---C   GATCG--- 5' 		AsuNHI, BmtI,  BspOI, , LlaG2I, NheI, PstNHI
AceIII 2569 Anabaena cedrorum 5' CAGCTC
3' GTCGAG 		5' ---CAGCTCN5N   NNNN--- 3'
3' ---GTCGAGN5NNNNN   --- 5' 		— None as of May 2010 —
AciI[11][22] 21 Arthrobacter citreus 5' CCGC
3' GGCG 		5' ---C   CGC--- 3'
3' ---GGC   G--- 5' 		SsiI
AclI[23] 2181 Acinetobacter calcoaceticus M4 5' AACGTT
3' TTGCAA 		5' ---AA   CGTT--- 3'
3' ---TTGC   AA--- 5' 		Psp1406I
AclNI 2667 Acinetobacter calcoaceticus N20 5' ACTAGT
3' TGATCA 		5' ---A   CTAGT--- 3'
3' ---TGATC   A--- 5' 		AhlI, BcuI, SpeI
AclWI 2668 Acinetobacter calcoaceticus W2131 5' GGATC
3' CCTAG 		5' ---GGATCN3N   N--- 3'
3' ---CCTAGN3NN   --- 5' 		AlwI, BinI,  BpuFI, BsrWI,  BspPI, BstH9I,  Bst31TI,  EacI,  Ral8I 
AcoI 11822 Acinetobacter calcoaceticus 5' YGGCCR
3' RCCGGY 		5' ---Y   GGCCR--- 3'
3' ---RCCGG   Y--- 5' 		EaeI, Bfi89I, CfrI, EcoHK31I
AcpI 22 Acidiphilium cryptum 25H 5' TTCGAA
3' AAGCTT 		5' ---TT   CGAA--- 3'
3' ---AAGC   TT--- 5' 		Asp10HI, Bpu14I, Bsp119I, BstBI, Csp45I, FspII, MlaI, NspV, SspRFI
AcpII 23 Acidiphilium cryptum 25H 5' CCAN5TGG
3' GGTN5ACC 		5' ---CCANNNN   NTGG--- 3'
3' ---GGTN   NNNNACC--- 5' 		AccB7I, Asp10HII, BasI, Esp1396I, PflBI, PflMI, Van91I
AcrII 25 Anabaenopsis circularis 5' GGTNACC
3' CCANTGG 		5' ---G   GTNACC--- 3'
3' ---CCANTG   G--- 5' 		AspAI, Bse64I, BseT9I, BstEII, BstPI, Eco91I, EcoO65I, PspEI
AcsI[24] 2184 Arthrobacter citreus 310 5' RAATTY
3' YTTAAR 		5' ---R   AATTY--- 3'
3' ---YTTAA   R--- 5' 		ApoI,  CfaI,  FsiI, XapI
AcuI 5534 Acinetobacter calcoaceticus 5' CTGAAG
3' GACTTC 		5' ---CTGAAGN13NNN   --- 3'
3' ---GACTTCN13N   NN--- 5' 		BspKT5I, Eco57I
AcvI 5359 Aeromonas caviae 5' CACGTG
3' GTGCAC 		5' ---CAC   GTG--- 3'
3' ---GTG   CAC--- 5' 		BbrPI, BcoAI, Eco72I, PmaCI, PmlI, PspCI
AcyI[25] 31 Anabaena cylindrica 5' GRCGYC
3' CYGCRG 		5' ---GR   CGYC--- 3'
3' ---CYGC   RG--- 5' 		AhaII, AosII, BbiII, BsaHI, BstACI, Hin1I, HgiI, Hsp92I, Msp17I
AdeI 2991 Alcaligenes denitrificans Ss 3-028 5' CACNNNGTG
3' GTGNNNCAC 		5' ---CACNNN   GTG--- 3'
3' ---GTG   NNNCAC--- 5' 		BstIZ316I, DraIII
AeuI 33 Achromobacter eurydice 5' CCWGG
3' GGWCC 		5' ---CC   WGG--- 3'
3' ---GGW   CC--- 5' 		AglI, AjnI, BseBI, BstNI, BstOI, Bst2UI, EcoRII, SleI, SspAI
AfaI[26] 37 Acidiphilium facilis 28H 5' GTAC
3' CATG 		5' ---GT   AC--- 3'
3' ---CA   TG--- 5' 		Csp6I, CviQI, CviRII, HpyBI, PabI, PlaAII, RsaI, RsaNI
Afa16RI 34 Acidiphilium sp. 16R 5' CGATCG
3' GCTAGC 		5' ---CGAT   CG--- 3'
3' ---GC   TAGC--- 5' 		Afa22MI, BspCI, EagBI, MvrI, NblI, Ple19I, PvuI, Psu161I, RshI, XorII
Afa22MI 35 Acidocella facilis 5' CGATCG
3' GCTAGC 		5' ---CGAT   CG--- 3'
3' ---GC   TAGC--- 5' 		Afa16RI, BspCI, EagBI, ErhB9I, NblI, Ple19I, Psu161I, PvuI, RshI
AfeI[27] 2669 Alcaligenes faecalis T2774 5' AGCGCT
3' TCGCGA 		5' ---AGC   GCT--- 3'
3' ---TCG   CGA--- 5' 		AitI, Aor51H, Eco47III, FunI
AfiI 10489 Anoxybacillus flavithermus 5' CCN7GG
3' GGN7CC 		5' ---CCNNNNN   NNGG--- 3'
3' ---GGNN   NNNNNCC--- 5' 		Bsc4I, BseLI, BslI, BflI, Bsc107I, BsiYI, Bst22I
AflI[28] Anabaena flos-aquae 5' GGWCC
3' CCWGG 		5' ---G   GWCC--- 3'
3' ---CCWG   G--- 5' 		Asp745I, BamNI, BcuAI, CauI, Csp68KI, DsaIV, Eco47I, SinI
AflII[28][29][30] 39 Anabaena flos-aquae 5' CTTAAG
3' GAATTC 		5' ---C   TTAAG--- 3'
3' ---GAATT   C--- 5' 		BfrI, BspTI, Bst98I, BstAFI, BstPZ740I, Esp4I, MspCI, Vha464I
AflIII[28][10] 40 Anabaena flos-aquae 5' ACRYGT
3' TGYRCA 		5' ---A   CRYGT--- 3'
3' ---TGYRC   A--- 5' 		 Asp90I 
AgeI[11][31] 42 Agrobacterium gelatinovorum 5' ACCGGT
3' TGGCCA 		5' ---A   CCGGT--- 3'
3' ---TGGCC   A--- 5' 		AsiAI, AsiGI, BshTI, CsiAI, CspAI, PinAI
AglI[32] 6652 Arthrobacter globiformis 5' CCWGG
3' GGWCC 		5' ---CC   WGG--- 3'
3' ---GGW   CC--- 5' 		AeuI, Bse16I, Bse17I, Bse24I, BshGI, EcoRII, SleI, SniI, SslI
AgsI Agrococcus sp. 25 5' TTSAA
3' AASTT 		5' ---TTS   AA--- 3'
5' ---AA   STT--- 3' 		None as of 4 May 2019
AhaI 45 Alteromonas haloplanktis B8 5' CCSGG
3' GGSCC 		5' ---CC   SGG--- 3'
3' ---GGS   CC--- 5' 		AseII, BcnI,  BpuMI,  CauII, Eco1831I, EcoHI, HgiS22I, NciI
AhaII Aphanothece halophytica 5' GRCGYC
3' CYGCRG 		5' ---GR   CGYC--- 3'
3' ---CYGC   RG--- 5' 		AcyI, AstWI, AsuIII, BsaHI, BstACI, Hin1I, HgiI, HgiDI, HgiHII, PamII
AhaIII[14][29][30][33] Aphanothece halophytica 5' TTTAAA
3' AAATTT 		5' ---TTT   AAA--- 3'
3' ---AAA   TTT--- 5' 		DraI, PauAII, SruI
AhaB8I Aphanothece halophytica B8 5' GGTACC
3' CCATGG 		5' ---G   GTACC--- 3'
3' ---CCATG   G--- 5' 		Acc65I, Asp718I, KpnI, SthI
AhdI[34][35] Aeromonas hydrophila 5' GACN5GTC
3' CTGN5CAG 		5' ---GACNNN   NNGTC--- 3'
3' ---CTGNN   NNNCAG--- 5' 		AspEI,  BmeRI,  BspOVI, DriI, Eam1105I, EclHKI, NruGI
AhlI 4838 Alteromonas haloplanktis SP 5' ACTAGT
3' TGATCA 		5' ---A   CTAGT--- 3'
3' ---TGATC   A--- 5' 		AclNI, BcuI, SpeI
AhyI 49 Aeromonas hydrophila 5' CCCGGG
3' GGGCCC 		5' ---C   CCGGG--- 3'
3' ---GGGCC   C--- 5' 		Cfr9I, CfrJ4I, EaeAI, EclRI, PaeBI, SmaI, TspMI, XmaI, XmaCI
AitI 54 Aquaspirillum itersonii 5' AGCGCT
3' TCGCGA 		5' ---AGC   GCT--- 3'
3' ---TCG   CGA--- 5' 		AfeI, Aor51H, Eco47III, FunI
AjiI 10919 Acinetobacter johnsonii RFL47 5' CACGTC
3' GTGCAG 		5' ---CAC   GTC--- 3'
3' ---GTG   CAG--- 5' 		BmgBI, BtrI
AjnI 7185 Acinetobacter johnsonii R2 5' CCWGG
3' GGWCC 		5' ---   CCWGG--- 3'
3' ---GGWCC   --- 5' 		AorI, ApaORI, ApyI, EcoRII, MvaI, Psp6I, PspGI, SleI, SspAI
AjoI 2604 Acinetobacter johnsonii 35 5' CTGCAG
3' GACGTC 		5' ---CTGCA   G--- 3'
3' ---G   ACGTC--- 5' 		ApiI, BloHII, BspMAI, CfrA4I, CfuII, PstI, SalPI, SflI, Srl5DI
AjuI 7740 Acinetobacter junii RFL46 5' GAAN7TTGG
3'CTTN7AACC 		5' ---NNNNN   NN6GAAN7TTGGN5NNNNNN   --- 3'
3' ---   NNNNNNN6CTTN7AACCN5N   NNNNN--- 5' 		None as of 28 Oct. 2020
AleI 5791 Aureobacterium liquefaciens 5' CACN4GTG
3' GTGN4CAC 		5' ---CACNN   NNGTG--- 3'
3' ---GTGNN   NNCAC--- 5' 		OliI
AlfI 6110 Acinetobacter lwoffii BH 32 5' GCAN6TGC
3' CGTN6ACG 		5' ---GCAN6TGCN9NNN   --- 3'
3' ---CGTN6ACGN9N   NN--- 5' 		None as of May 2010
AliI Acetobacter liquefaciens 5' GGATCC
3' CCTAGG 		5' ---G   GATCC--- 3'
3' ---CCTAG   G--- 5' 		AccEBI, BamHI, Bce751I, Bsp98I, BspAAIII, Nsp29132II, Pfl8I
AliAJI 59 Acetobacter liquefaciens AJ 2881 5' CTGCAG
3' GACGTC 		5' ---CTGCA   G--- 3'
3' ---G   ACGTC--- 5' 		ApiI, Asp713I, BspMAI, CflI, CstI, MhaAI, PstI, SalPI, Sst12I, YenI
AloI[36][37] 2812 Acinetobacter lwoffii Ks 4-8 5' GAACN6TCC
3' CTTGN6AGG 		5' ---GAACN6TCCN6NNNNNN   --- 3'
3' ---CTTGN6AGGN6N   NNNNN--- 5' 		None as of May 2010
AluI[12][14][38][39][40][41] 61 Arthrobacter luteus 5' AGCT
3' TCGA 		5' ---AG   CT--- 3'
3' ---TC   GA--- 5' 		AluBI, MltI
AluBI 16189 Arthrobacter luteus B 5' AGCT
3' TCGA 		5' ---AG   CT--- 3'
3' ---TC   GA--- 5' 		AluI, MltI
AlwI 65 Acinetobacter lwoffii 5' GGATC
3' CCTAG 		5' ---GGATCN3N   N--- 3'
3' ---CCTAGN3NN   --- 5' 		AclWI, BinI, BspPI,  BsrWI,  BstH9I,  BthII, Bth617I,  EacI
Alw21I Acinetobacter lwoffii RFL21 5' GWGCWC
3' CWCGWG 		5' ---GWGCW   C--- 3'
3' ---C   WCGWG--- 5' 		AspHI, Bbv12I, Bsh45I, BsiHKAI, Bsm6I,  HgiAI, MspV281I
Alw26I[42] 63 Acinetobacter lwoffii RFL26 5' GTCTC
3' CAGAG 		5' ---GTCTCN   NNNN--- 3'
3' ---CAGAGNNNNN   --- 5' 		 BcoDI, BscQII,   BsmAI, BsoMAI,  BstMAI 
Alw44I Acinetobacter lwoffii RFL44 5' GTGCAC
3' CACGTG 		5' ---G   TGCAC--- 3'
3' ---CACGT   G--- 5' 		ApaLI, SnoI, VneI
AlwNI[43] Acinetobacter lwoffii N 5' CAGNNNCTG
3' GTCNNNGAC 		5' ---CAGNNN   CTG--- 3'
3' ---GTC   NNNGAC--- 5' 		CaiI
AlwXI 67 Acinetobacter lwoffii X 5' GCAGC
3' CGTCG 		5' ---GCAGCN7N   NNNN--- 3'
3' ---CGTCGN7NNNNN   --- 5' 		BbvI, BseKI, BseXI, Bsp423I, Bst12I, Bst71I, BstV1I
Ama87I Alteromonas macleodii 87 5' CYCGRG
3' GRGCYC 		5' ---C   YCGRG--- 3'
3' ---GRGCY   C--- 5' 		AquI, AvaI,  BmeT110I,  BsiHKCI, BsoBI, Eco88I, Nli3877I, NspSAI
AmaCSI 26714 Arthrospira maxima CS-328 5' GCTCCA
3' CGAGGT 		5' ---GCTCCAN8NNN   --- 3'
3' ---CGAGGTN8N   NN--- 5' 		None as of 4 May 2018
AocI 74 Anabaena sp. 5' CCTNAGG
3' GGANTCC 		5' ---CC   TNAGG--- 3'
3' ---GGANT   CC--- 5' 		AyI, Bse21I, Bsu36I, Eco81I, Lmu60I, OaNI, MstII, SauI, SshAI
AocII Anabaena sp. 5' GDGCHC
3' CHCGDG 		5' ---GDGCH   C--- 3'
3' ---C   HCGDG--- 5' 		BmyI, BsoCI, Bsp1286I, BspLS2I, MhlI, NspII, SduI
AorI 77 Acetobacter aceti orleanensis 5' CCWGG
3' GGWCC 		5' ---CC   WGG--- 3'
3' ---GGW   CC--- 5' 		BseBI, BstNI, BstOI, Bst2UI, EcoRII, MvaI, Sth117I, Tai
Aor13HI[44] Acidiphilium organovorum 13H 5' TCCGGA
3' AGGCCT 		5' ---T   CCGGA--- 3'
3' ---AGGCC   T--- 5' 		AccIII, BbvAIII, BlfI, BseAI, BsiMI, BspEI, CauB3I, Kpn2I, MroI, PtaI
Aor51HI[45] 76 Acidiphilium organovorum 51H 5' AGCGCT
3' TCGCGA 		5' ---AGC   GCT--- 3'
3' ---TCG   CGA--- 5' 		AfeI, AitI, Eco47III, FunI
AosI Anabaena oscillarioides 5' TGCGCA
3' ACGCGT 		5' ---TGC   GCA--- 3'
3' ---ACG   CGT--- 5' 		Acc16I, AviII, FdiII, FspI, MstI, NsbI, PamI, Pun14627I
AosII Anabaena oscillarioides 5' GRCGYC
3' CYGCRG 		5' ---GR   CGYC--- 3'
3' ---CYGC   RG--- 5' 		AcyI, AstWI, BbiII, BsaHI, BstACI, Hin1I, HgiI, HgiGI, Msp17I, PamII
ApaI[11][30][46] Acetobacter pasteurianus pasteurianus 5' GGGCCC
3' CCCGGG 		5' ---GGGCC   C--- 3'
3' ---C   CCGGG--- 5' 		Bsp120I, PpeI, PspOMI
ApaBI[47] Acetobacter pasteurianus B 5' GCAN5TGC
3' CGTN5ACG 		5' ---GCANNNNN   TGC--- 3'
3' ---CGT   NNNNNACG--- 5' 		BstAPI
ApaCI Acetobacter pasteurianus C 5' GGATCC
3' CCTAGG 		5' ---G   GATCC--- 3'
3' ---CCTAG   G--- 5' 		AliI, BamHI, BnaI, Bsp4009I, BstI, NspSAIV, Pfl8I, SolI, SurI
ApaLI[48][49] Acetobacter pasteurianus 5' GTGCAC
3' CACGTG 		5' ---G   TGCAC--- 3'
3' ---CACGT   G--- 5' 		Alw44I, SnoI, VneI
ApaORI 86 Acetobacter pasteurianus 5' CCWGG
3' GGWCC 		5' ---CC   WGG--- 3'
3' ---GGW   CC--- 5' 		AjnI, BstNI, BstOI, Bst1I, Bst2I, Fsp1604I, MvaI, Psp6I, PspGI
ApeKI[50] Aeropyrum pernix K1 5' GCWGC
3' CGWCG 		5' ---G   CWGC--- 3'
3' ---CGWC   G--- 5' 		AceI, SuiI, Taq52I, TseI
ApiI 2315 Arthrobacter picolinophilus 5' CTGCAG
3' GACGTC 		5' ---CTGCA   G--- 3'
3' ---G   ACGTC--- 5' 		Asp713I, Bsp63I, CfrA4I, PaePI, Pfl21I, Psp23I, PstI, SflI, Sst12I
ApoI[51] Arthrobacter protophormiae 5' RAATTY
3' YTTAAR 		5' ---R   AATTY--- 3'
3' ---YTTAA   R--- 5' 		AcsI, CfaI,  FsiI, XapI, EcoRI
AplI 25962 Arthrospira platensis NIES-39 5' CTGCAG
3' GACGTC 		5' ---CTGCA   G--- 3'
3' ---G   ACGTC--- 5' 		See this site for a complete list.
ApyI 93 Arthrobacter pyridinolis 5' CCWGG
3' GGWCC 		5' ---CC   WGG--- 3'
3' ---GGW   CC--- 5' 		BciBII, BptI, BseBI, BstNI, BstOI, Bst2UI, Bst38I, Bst100I, MvaI
ApyPI 14756 Arcanobacterium pyogenes 5' ATCGAC
3' TAGCTG 		5' ---ATCGACN17NNN   --- 3'
3' ---TAGCTGN17N   NN--- 5' 		None as of 4 August 2019
AquI Agmenellum quadruplicatum PR-6 5' CYCGRG
3' GRGCYC 		5' ---C   YCGRG--- 3'
3' ---GRGCY   C--- 5' 		BcoI,  BmeT110I,  BsmAI, BsoMAI, BsoBI, BstSI, Eco27kI, OfoI
AquII 20238 Agmenellum quadruplicatum PR-6 5' GCCGNAC
3' CGGCNTG 		5' ---GCCGNACN17NNN   --- 3'
3' ---CGGCNTGN17N   NN--- 5' 		None as of 4 August 2019
AquIII 20239 Agmenellum quadruplicatum PR-6 5' GAGGAG
3' CTCCTC 		5' ---GAGGAGN17NNN   --- 3'
3' ---CTCCTCN17N   NN--- 5' 		BseRI
AquIV 20240 Agmenellum quadruplicatum PR-6 5' GRGGAAG
3' CYCCTTC 		5' ---GRGGAAGN16NNN   --- 3'
3' ---CYCCTTCN16N   NN--- 5' 		None as of 4/9/19
ArsI 19405 Arthrobacter sp. NTS 5' GACN6TTYG
3' CTGN6AARC 		5' ---NNNNN   NN7GACN6TTYGN5NNNNNN   --- 3'
3' ---   NNNNNNN7CTGN6AARCN5N   NNNNN--- 5' 		None as of Oct. 28 2020
AscI[11][52] Arthrobacter sp. 5' GGCGCGCC
3' CCGCGCGG 		5' ---GG   CGCGCC--- 3'
3' ---CCGCGC   GG--- 5' 		 PalAI, SgsI 
AseI[53] 96 Aquaspirillum serpens 5' ATTAAT
3' TAATTA 		5' ---AT   TAAT--- 3'
3' ---TAAT   TA--- 5' 		AsnI, BpoAI, PshBI, Sru4DI, VspI
AseII[53] 97 Aquaspirillum serpens 5' CCSGG
3' GGSCC 		5' ---CC   SGG--- 3'
3' ---GGS   CC--- 5' 		AhaI, AsuC2I, BcnI, CauII, EcoHI, HgiS22I, Kpn49kII, Mgl14481I, NciI
AsiI Azotobacter sp. 5' GGATCC
3' CCTAGG 		5' ---G   GATCC--- 3'
3' ---CCTAG   G--- 5' 		ApaCI, BamHI, BnaI, Bsp4009I, BstI, OkrAI, Pfl8I, SurI, Uba4009I
AsiAI 2853 Arthrobacter sp. A7359 5' ACCGGT
3' TGGCCA 		5' ---A   CCGGT--- 3'
3' ---TGGCC   A--- 5' 		AgeI, AsiGI, BshTI, CsiAI, CspAI, PinAI
AsiGI 10828 Arthrobacter sp. G 5' ACCGGT
3' TGGCCA 		5' ---A   CCGGT--- 3'
3' ---TGGCC   A--- 5' 		AgeI, AsiAI, BshTI, CsiAI, CspAI, PinAI
AsiSI Arthrobacter sp. 5' GCGATCGC
3' CGCTAGCG 		5' ---GCGAT   CGC--- 3'
3' ---CGC   TAGCG--- 5' 		 RgaI, SfaAI, , SgfI
Asi256I 18472 Arthrobacter sp. Ck256 5' GATC
3' CTAG 		5' ---G   ATC--- 3'
3' ---CTA   G--- 5' 		See this site for a complete list.
Asi372I 15803 Arthrobacter sp. Mn372 5' ATGCAT
3' TACGTA 		5' ---ATGCA   T--- 3'
3' ---T   ACGTA--- 5' 		Ppu10I, EcoT22I, Mph1103I, NsiI, Zsp2I, BfrBI, Csp68KIII, PinBI, SepI, SspD5II
AsnI[54] 98 Arthrobacter sp. N-CM 5' ATTAAT
3' TAATTA 		5' ---AT   TAAT--- 3'
3' ---TAAT   TA--- 5' 		AseI, BpoAI, PshBI, Sru4DI, VspI
AspI[55] Achromobacter sp. 699 5' GACNNNGTC
3' CTGNNNCAG 		5' ---GACN   NNGTC--- 3'
3' ---CTGNN   NCAG--- 5' 		AtsI, PflFI, PsyI, TelI, Tth111I
Asp10HI Acidiphilium sp. 10H 5' TTCGAA
3' AAGCTT 		5' ---TT   CGAA--- 3'
3' ---AAGC   TT--- 5' 		AsuII, BspT104I, BstBI, CbiI, Csp68KII, PlaII, PpaAI, Ssp1I
Asp10HII 100 Acidiphilium sp. 10H 5' CCAN5TGG
3' GGTN5ACC 		5' ---CCANNNN   NTGG--- 3'
3' ---GGTN   NNNNACC--- 5' 		AccB7I, AcpII, BasI, Esp1396I, PflBI, PflMI, Van91I
Asp26HI 111 Acidiphilium sp. 26H 5' GAATGC
3' CTTACG 		5' ---GAATGCN   --- 3'
3' ---CTTAC   GN--- 5' 		Asp27HI, Asp35HI, Asp36HI, BsaMI, BscCI, BsmI, PctI
Asp27HI 112 Acidiphilium sp. 27H 5' GAATGC
3' CTTACG 		5' ---GAATGCN   --- 3'
3' ---CTTAC   GN--- 5' 		Asp35HI, Asp36HI, Asp40HI,  BmaHI,  BsaMI, BscCI, BsmI
Asp35HI 117 Acidiphilium sp. 35H 5' GAATGC
3' CTTACG 		5' ---GAATGCN   --- 3'
3' ---CTTAC   GN--- 5' 		Asp36HI, Asp40HI, Asp50HI, BsaMI, BscCI, BsmI, Mva1269I
Asp36HI 118 Acidiphilium sp. 36H 5' GAATGC
3' CTTACG 		5' ---GAATGCN   --- 3'
3' ---CTTAC   GN--- 5' 		Asp40HI, Asp50HI,  BmaHI,  BscCI, BsmI, Mva1269I, PctI
Asp40HI 120 Acidiphilium sp. 40H 5' GAATGC
3' CTTACG 		5' ---GAATGCN   --- 3'
3' ---CTTAC   GN--- 5' 		Asp27HI, Asp36HI, Asp50HI, BsaMI, BscCI, BsmI, Mva1269I
Asp50HI 122 Acidiphilium sp. 50H 5' GAATGC
3' CTTACG 		5' ---GAATGCN   --- 3'
3' ---CTTAC   GN--- 5' 		Asp26HI, Asp35HI, Asp36HI, BsaMI, BscCI, BsmI, Mva1269I
Asp700I[56] Achromobacter sp. 700 5' GAAN4TTC
3' CTTN4AAG 		5' ---GAANN   NNTTC--- 3'
3' ---CTTNN   NNAAG--- 5' 		BbvAI, MroXI, PdmI, XmnI
Asp713I 131 Achromobacter sp. 713 5' CTGCAG
3' GACGTC 		5' ---CTGCA   G--- 3'
3' ---G   ACGTC--- 5' 		AjoI, AliAJI, BloHII, CfrA4I, Ecl37kI, MhaAI, PstI, SflI, Srl5DI, YenI
Asp718I[57] Achromobacter sp. 718 5' GGTACC
3' CCATGG 		5' ---G   GTACC--- 3'
3' ---CCATG   G--- 5' 		Acc65I, AhaB8I, KpnI, SthI
Asp745I Achromobacter sp. 745 5' GGWCC
3' CCWGG 		5' ---G   GWCC--- 3'
3' ---CCWG   G--- 5' 		Bme18I, BsrAI, CauI, Eco47I, ErpI, FdiI, SinI, VpaK11AI, VpaK11BI
AspAI Alcaligenes sp. 5' GGTNACC
3' CCANTGG 		5' ---G   GTNACC--- 3'
3' ---CCANTG   G--- 5' 		AcrII, Bse64I, BseT10I, BstEII, BstPI, Eco91I, EcoO65I, PspEI
AspA2I 6959 Arthrobacter sp. A2 5' CCTAGG
3' GGATCC 		5' ---C   CTAGG--- 3'
3' ---GGATC   C--- 5' 		AvrBII, AvrII, BlnI, BspA2I, XmaJI
AspEI[58] Aureobacterium sp. 5' GACN5GTC
3' CTGN5CAG 		5' ---GACNNN   NNGTC--- 3'
3' ---CTGNN   NNNCAG--- 5' 		AhdI,  BmeRI,  BspOVI, DriI, Eam1105I, EclHKI, NruGI
AspHI[59] Achromobacter sp. H 5' GWGCWC
3' CWCGWG 		5' ---GWGCW   C--- 3'
3' ---C   WCGWG--- 5' 		Alw21I, Bbv12I, Bsh45I, BsiHKAI,  Bsm6I,  HgiAI, MspV281I
AspLEI Arthrobacter sp. LE3860 5' GCGC
3' CGCG 		5' ---GCG   C--- 3'
3' ---C   GCG--- 5' 		BspLAI, BstHHI, CfoI, FnuDIII, HhaI, Hin6I, HinP1I, HsoI, HspAI, SciNI
AspMI 2977 Acinetobacter sp. M 5' AGGCCT
3' TCCGGA 		5' ---AGG   CCT--- 3'
3' ---TCC   GGA--- 5' 		AatI, Eco147I, GdiI, PceI, SarI, Sru30DI, SseBI, SteI, StuI
AspMDI Alcaligenes sp. MD1 5' GATC
3' CTAG 		5' ---   GATC--- 3'
3' ---CTAG   --- 5' 		BfuCI, Bsp143I, BstMBI, DpnII, Kzo9I, MboI, NdeII, Sau3AI
AspNI Anabaena sp. J3 5' GGNNCC
3' CCNNGG 		5' ---GGN   NCC--- 3'
3' ---CCN   NGG--- 5' 		 BmiI,  BscBI, BspLI, NlaIV, PspN4I
AspS9I Arthrobacter sp. S9 5' GGNCC
3' CCNGG 		5' ---G   GNCC--- 3'
3' ---CCNG   G--- 5' 		AsuI, AvcI, Bac36I, Bal228I, FmuI, NspIV, PspPI, Sau96I
AssI 4930 Arthrobacter sp. 5' AGTACT
3' TCATGA 		5' ---AGT   ACT--- 3'
3' ---TCA   TGA--- 5' 		Acc113I,  BmcAI, Bpa34I,  DpaI, Eco255I, RflFII, ScaI, ZrmI
AstWI Anabaena sp. 5' GRCGYC
3' CYGCRG 		5' ---GR   CGYC--- 3'
3' ---CYGC   RG--- 5' 		AcyI, AsuIII, BsaHI, BstACI, Hin1I, HgiI, HgiDI, HgiGI, Msp17I
AsuI[60] Anabaena subcylindrica 5' GGNCC
3' CCNGG 		5' ---G   GNCC--- 3'
3' ---CCNG   G--- 5' 		AspS9I, AvcI, CcuI, Cfr13I, FmuI, MaeK81II, Nsp7121I, PspPI, UnbI
AsuII[61] Anabaena subcylindrica 5' TTCGAA
3' AAGCTT 		5' ---TT   CGAA--- 3'
3' ---AAGC   TT--- 5' 		AcpI, Bpu14I, Bsp119I, BspT104I, Csp45I, FspII, LspI, NspV, SfuI
AsuIII Anabaena subcylindrica 5' GRCGYC
3' CYGCRG 		5' ---GR   CGYC--- 3'
3' ---CYGC   RG--- 5' 		AcyI, AsuIII, BbiII, BsaHI, BstACI, Hin1I, HgiHII, Hsp92I, Msp17I
AsuC2I 2901 Actinobacillus suis C2 5' CCSGG
3' GGSCC 		5' ---CC   SGG--- 3'
3' ---GGS   CC--- 5' 		AhaI, AseII, BcnI, Eco1831I, EcoHI, Kpn49kII, Mgl14481I, NciI
AsuHPI[62] 2811 Actinobacillus suis HP 5' GGTGA
3' CCACT 		5' ---GGTGAN6NN   --- 3'
3' ---CCACTN6N   N--- 5' 		HphI, SspD5I
AsuNHI[62] Actinobacillus suis NH 5' GCTAGC
3' CGATCG 		5' ---G   CTAGC--- 3'
3' ---CGATC   G--- 5' 		AceII, BmtI,  BspOI,  LlaG2I, NheI, PstNHI
AtsI Aureobacterium testaceum 4842 5' GACNNNGTC
3' CTGNNNCAG 		5' ---GACN   NNGTC--- 3'
3' ---CTGNN   NCAG--- 5' 		AspI, PflFI, PsyI, TelI, Tth111I
AvaI[14][63][64] Anabaena variabilis 5' CYCGRG
3' GRGCYC 		5' ---C   YCGRG--- 3'
3' ---GRGCY   C--- 5' 		AquI, Ama87I, BsiHKCI, BsoBI, BspLU4I, Eco88I, NspIII, PlaAI
AvaII[12][14][41][63][64] Anabaena variabilis 5' GGWCC
3' CCWGG 		5' ---G   GWCC--- 3'
3' ---CCWG   G--- 5' 		Bme18I, Bme216I, BsrAI, Eco47I, Kzo49I, Psp03I, SmuEI, VpaK11AI
AvcI Actinomyces violaceoniger cristalomycini 5' GGNCC
3' CCNGG 		5' ---G   GNCC--- 3'
3' ---CCNG   G--- 5' 		AspS9I, BshKI, BsiZI, Bsp1894I, BspBII, BspF4I, Bsu54I, Pde12I
AviII Anabaena variabillis (halle) 5' TGCGCA
3' ACGCGT 		5' ---TGC   GCA--- 3'
3' ---ACG   CGT--- 5' 		Acc16I, AosI, FdiII, FspI, MstI, NsbI, PamI, Pun14627I
AvrII[11][29] 173 Anabaena variabilis UW 5' CCTAGG
3' GGATCC 		5' ---C   CTAGG--- 3'
3' ---GGATC   C--- 5' 		AspA2I, AvrBII, BlnI, BspA2I, XmaJI
AvrBII 171 Arthrobacter variabilis 5' CCTAGG
3' GGATCC 		5' ---C   CTAGG--- 3'
3' ---GGATC   C--- 5' 		AspA2I, AvrII, BlnI, BspA2I, XmaJI
AxyI[65] 174 Acetobacter xylinus 5' CCTNAGG
3' GGANTCC 		5' ---CC   TNAGG--- 3'
3' ---GGANT   CC--- 5' 		AocI, BliHKI, Bse21I, BspR7I, Bsu36I, CvnI, Eco81I, Lmu60I

§ An HF version of this enzyme is available

This list is incomplete; you can help by expanding it.


Notes

  1. ↑ "Letter: A suggested nomenclature for bacterial host modification and restriction systems and their enzymes". J. Mol. Biol. 81 (3): 419–23. December 1973. doi:10.1016/0022-2836(73)90152-6. PMID 4588280. 
  2. ↑ "A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes". Nucleic Acids Res. 31 (7): 1805–12. April 2003. doi:10.1093/nar/gkg274. PMID 12654995. 
  3. ↑ "3. Protein Structure and Function". Biochemistry. San Francisco: W. H. Freeman. 2002. ISBN 0-7167-4684-0. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Search&db=books&doptcmdl=GenBookHL&term=stryer%5Bbook%5D+AND+215168%5Buid%5D&rid=stryer.chapter.280. 
  4. ↑ Anfinsen C.B. (1973). "Principles that Govern the Folding of Protein Chains". Science 181 (4096): 223–30. doi:10.1126/science.181.4096.223. PMID 4124164. Bibcode: 1973Sci...181..223A. 
  5. ↑ "Specificity of restriction endonucleases and DNA modification methyltransferases a review (Edition 3)". Gene 92 (1–2): 1–248. August 1990. doi:10.1016/0378-1119(90)90486-B. PMID 2172084. 
  6. ↑ "Structure and function of type II restriction endonucleases". Nucleic Acids Res. 29 (18): 3705–27. September 2001. doi:10.1093/nar/29.18.3705. PMID 11557805. 
  7. ↑ "AarI, a restriction endonuclease from Arthrobacter aurescens SS2-322, which recognizes the novel non-palindromic sequence 5'-CACCTGC(N)4/8-3'". Nucleic Acids Res 30 (21): 123e–123. November 2002. doi:10.1093/nar/gnf122. PMID 12409482. 
  8. ↑ 8.0 8.1 "New restriction endonucleases from Acetobacter aceti and Bacillus aneurinolyticus". Nucleic Acids Res 10 (19): 5747–52. October 1982. doi:10.1093/nar/10.19.5747. PMID 6292849. 
  9. ↑ "Cloning and expression of AatII restriction-modification system in Escherichia coli". Gene 185 (1): 105–9. January 1997. doi:10.1016/S0378-1119(96)00641-5. PMID 9034320. 
  10. ↑ 10.0 10.1 Roberts RJ (January 1983). "Restriction and modification enzymes and their recognition sequences". Nucleic Acids Res 11 (1): r135–69. PMID 6306557. 
  11. ↑ 11.0 11.1 11.2 11.3 11.4 11.5 "The Fidelity Index provides a systematic quantitation of star activity of DNA restriction endonucleases". Nucleic Acids Res 36 (9): e50. May 2008. doi:10.1093/nar/gkn182. PMID 18413342. 
  12. ↑ 12.0 12.1 12.2 12.3 "Type II restriction endonucleases cleave single-stranded DNAs in general". Nucleic Acids Res 13 (16): 5747–60. August 1985. doi:10.1093/nar/13.16.5747. PMID 2994012. 
  13. ↑ "Hydrolysis by restriction endonucleases at their DNA recognition sequences substituted with mismatched base pairs". Nucleic Acids Res 14 (11): 4407–20. June 1986. PMID 3012472. 
  14. ↑ 14.0 14.1 14.2 14.3 14.4 "Alteration of apparent restriction endonuclease recognition specificities by DNA methylases". Nucleic Acids Res 12 (13): 5165–73. July 1984. doi:10.1093/nar/12.13.5165. PMID 6087274. 
  15. ↑ "Restriction endonuclease cleavage of 5-methyl-deoxycytosine hemimethylated DNA at high enzyme-to-substrate ratios". Nucleic Acids Res 21 (3): 681–6. February 1993. doi:10.1093/nar/21.3.681. PMID 8441677. 
  16. ↑ "Determination of the cleavage site of restriction enzyme, AccII, using synthetic oligonucleotide". Agric Biol Chem 48 (2): 531–2. 1984. doi:10.1271/bbb1961.48.531. 
  17. ↑ "AccIII, a new restriction endonuclease from Acinetobacter calcoaceticus". Nucleic Acids Res 13 (24): 8685–94. December 1985. doi:10.1093/nar/13.24.8685. PMID 3001647. 
  18. ↑ "Many type IIs restriction endonucleases interact with two recognition sites before cleaving DNA". J Biol Chem 277 (6): 4024–33. February 2002. doi:10.1074/jbc.M108441200. PMID 11729187. 
  19. ↑ "Determination of substrate specificity of restriction endonuclease Acc65I". Sib Biol J 1: 59–60. 1991. 
  20. ↑ "Screening of strains producing restriction endonucleases in Lake Baikal". Izv Sib Otd Akad Nauk SSSR 1: 35–37. 1990. 
  21. ↑ "AccBSI – a novel restriction endonuclease from Acinetobacter calcoaceticus BS (Article in russian)". Prikl Biokhim Mikrobiol 33 (5): 556–8 (Translation into english in pp. 496–8). September–October 1997. PMID 9441298. 
  22. ↑ "AciI, a unique restriction endonuclease from Arthrobacter citreus which recognizes 5' CCGC3'". Nucleic Acids Res 18 (19): 5911. October 1990. doi:10.1093/nar/18.19.5911. PMID 2170952. 
  23. ↑ "AclI, a new restriction endonuclease from Acinetobacter calcoaceticus recognizing 5'-AA^CGTT-3'". Nucleic Acids Res 20 (14): 3787. July 1992. doi:10.1093/nar/20.14.3787. PMID 1322531. 
  24. ↑ "AcsI, a new restriction endonuclease from Arthrobacter citreus 310 recognizing 5'-Pu decreases AATTPy-3'". Nucleic Acids Res 20 (14): 3789. July 1992. doi:10.1093/nar/20.14.3789. PMID 1322532. 
  25. ↑ "A new sequence-specific endonuclease from Anabaena cylindrica". FEBS Lett 96 (1): 106–10. December 1978. doi:10.1016/0014-5793(78)81072-2. PMID 103749. 
  26. ↑ "Restriction endonuclease AfaI from Acidiphilium facilis, a new isoschizomer of RsaI: purification and properties". Biochim Biophys Acta 1009 (1): 83–6. September 1989. doi:10.1016/0167-4781(89)90082-1. PMID 2790034. 
  27. ↑ "Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases". Nucleic Acids Res 37 (22): 7612–22. December 2009. doi:10.1093/nar/gkp845. PMID 19820117. 
  28. ↑ 28.0 28.1 28.2 "Three restriction endonucleases from Anabaena flos-aquae". J Gen Microbiol 131 (4): 951–8. April 1985. doi:10.1099/00221287-131-4-951. PMID 2985742. 
  29. ↑ 29.0 29.1 29.2 "'Stop-codon-specific' restriction endonucleases: their use in mapping and gene manipulation". Gene 116 (1): 21–6. July 1992. doi:10.1016/0378-1119(92)90624-X. PMID 1628840. 
  30. ↑ 30.0 30.1 30.2 Roberts RJ (March 1982). "Restriction and modification enzymes and their recognition sequences". Nucleic Acids Res 10 (5): r117–44. doi:10.1093/nar/10.5.1770. PMID 6280143. 
  31. ↑ "A new restriction endonuclease from Agrobacterium gelatinovorum, a marine agrobacterium (AgeI)". Agric Biol Chem 53 (6): 1747–9. 1989. doi:10.1271/bbb1961.53.1747. 
  32. ↑ Sokolov NN (1995). "Search, isolation and study of restrictases" (in ru). Vestn Ross Akad Med Nauk (2): 47–51. PMID 7756931. 
  33. ↑ "AhaIII: A restriction endonuclease with a recognition sequence containing only A:T basepairs". FEBS Lett 143 (2): 296–300. July 1982. doi:10.1016/0014-5793(82)80120-8. PMID 6288466. 
  34. ↑ "Purification and characterisation of a novel DNA methyltransferase, M.AhdI". Nucleic Acids Res 31 (11): 2803–10. June 2003. doi:10.1093/nar/gkg399. PMID 12771207. 
  35. ↑ "Transcription regulation of the type II restriction-modification system AhdI". Nucleic Acids Res 36 (5): 1429–42. March 2008. doi:10.1093/nar/gkm1116. PMID 18203750. 
  36. ↑ "Characterization of AloI, a restriction-modification system of a new type". J Mol Biol 314 (2): 205–16. November 2001. doi:10.1006/jmbi.2001.5049. PMID 11718555. 
  37. ↑ "Generation of DNA cleavage specificities of type II restriction endonucleases by reassortment of target recognition domains". Proc Natl Acad Sci USA 104 (25): 10358–63. June 2007. doi:10.1073/pnas.0610365104. PMID 17553965. Bibcode: 2007PNAS..10410358J. 
  38. ↑ "'Single-stranded' DNA from phiX174 and M13 is cleaved by certain restriction endonucleases". Nature 257 (5525): 421–2. October 1975. doi:10.1038/257421a0. PMID 809717. Bibcode: 1975Natur.257..421B. 
  39. ↑ "A specific endonuclease from Arthrobacter luteus". J Mol Biol 102 (1): 157–65. March 1976. doi:10.1016/0022-2836(76)90079-6. PMID 1271462. 
  40. ↑ "A general method for the purification of restriction enzymes". Nucleic Acids Res 5 (7): 2373–80. July 1978. doi:10.1093/nar/5.7.2373. PMID 673857. 
  41. ↑ 41.0 41.1 "Digestion of highly modified bacteriophage DNA by restriction endonucleases". Nucleic Acids Res 10 (5): 1579–91. March 1982. doi:10.1093/nar/10.5.1579. PMID 6280151. 
  42. ↑ "Alw26I, Eco31I and Esp3I—type IIs methyltransferases modifying cytosine and adenine in complementary strands of the target DNA". Nucleic Acids Res 20 (19): 4981–5. October 1992. doi:10.1093/nar/20.19.4981. PMID 1408816. 
  43. ↑ "A unique type II restriction endonuclease from Acinetobacter lwoffi N". Nucleic Acids Res 15 (17): 7201. September 1987. doi:10.1093/nar/15.17.7201. PMID 2821501. 
  44. ↑ "Restriction endonuclease Aor13HI from Acidiphilium organovorum 13H, a new isoschizomer of BspMII: Purification and characterization". Biosci Biotechnol Biochem 57 (10): 1716–21. October 1993. doi:10.1271/bbb.57.1716. PMID 7764267. 
  45. ↑ "Isolation and identification of restriction endonuclease Aor51HI from Acidiphilium organovorum 51H". Nucleic Acids Res 20 (2): 365. January 1992. doi:10.1093/nar/20.2.365. PMID 1741262. 
  46. ↑ "A new restriction endonuclease from Acetobacter pasteurianus". Nucleic Acids Res 11 (13): 4409–15. July 1983. doi:10.1093/nar/11.13.4409. PMID 6306590. 
  47. ↑ "Some properties of restriction endonuclease ApaBI from Acetobacter pasteurianus". Biochim Biophys Acta 1162 (3): 323–5. March 1993. doi:10.1016/0167-4838(93)90297-5. PMID 8457597. 
  48. ↑ "Cloning and expression of the ApaLI, NspI, NspHI, SacI, ScaI, and SapI restriction-modification systems in Escherichia coli". Mol Gen Genet 260 (2–3): 226–31. Nov 1998. doi:10.1007/s004380050890. PMID 9862476. 
  49. ↑ "Adenine DNA methyltransferase M.CviRI expression accelerates apoptosis in baculovirus-infected insect cells". Virology 196 (2): 817–24. October 1993. doi:10.1006/viro.1993.1539. PMID 8372450. 
  50. ↑ "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1". DNA Res 6 (2): 83–101, 145–52. April 1999. doi:10.1093/dnares/6.2.83. PMID 10382966. 
  51. ↑ "ApoI, a unique restriction endonuclease from Arthrobacter protophormiae which recognizes 5' RAATTY-3'". Nucleic Acids Res. 20 (11): 2888. June 1992. doi:10.1093/nar/20.11.2888. PMID 1614876. 
  52. ↑ "Reactions of type II restriction endonucleases with 8-base pair recognition sites". J Biol Chem 274 (51): 36379–86. December 1999. doi:10.1074/jbc.274.51.36379. PMID 10593932. 
  53. ↑ 53.0 53.1 "AseI, a restriction endonuclease from Aquaspirillum serpens which recognizes 5'AT—TAAT3'". Nucleic Acids Res 16 (21): 10365. November 1988. doi:10.1093/nar/16.21.10365. PMID 3264065. 
  54. ↑ "AsnI: a novel class II restriction endonuclease from Arthrobacter sp., strain N-CM, recognizing 5'-AT/TAAT-3'". FEBS Lett 235 (1–2): 241–6. August 1988. doi:10.1016/0014-5793(88)81271-7. PMID 2841156. 
  55. ↑ "AspI, a novel isoschizomer of Tth111I from Achromobacter species 699 recognizing 5'-GACN/NNGTC-3'". Nucleic Acids Res 18 (11): 3422. June 1990. doi:10.1093/nar/18.11.3422. PMID 2162524. 
  56. ↑ "Asp700I, a novel isoschizomer of XmnI from Achromobacter species 700 recognizing 5'-GAANN/NNTTC-3'". Nucleic Acids Res 17 (21): 8879. November 1989. doi:10.1093/nar/17.21.8879. PMID 2587236. 
  57. ↑ "Cleavage by the restriction endonuclease Asp718, an isoschizomer of KpnI, is sensitive to Escherichia coli Dcm methylation". Nucleic Acids Res 15 (21): 9085. November 1987. doi:10.1093/nar/15.21.9085. PMID 2825125. 
  58. ↑ "AspEI, a novel Eam11051 isoschizomer from Aureobacterium species recognizing 5'-GACnnn/nnGTC-3'". Nucleic Acids Res 20 (14): 3782. July 1992. doi:10.1093/nar/20.14.3782. PMID 1641345. 
  59. ↑ "AspHI, a novel isoschizomer of HgiAI from Achromobacter species H recognizing 5'-GWGCW/C-3'". Nucleic Acids Res 17 (22): 9500. November 1989. doi:10.1093/nar/17.22.9500. PMID 2587281. 
  60. ↑ "The Isolation and Characterization of a Sequence-Specific Endonuclease from Anabaena subcylindrica". Biochem J 185 (1): 59–63. January 1980. doi:10.1042/bj1850059. PMID 6246880. 
  61. ↑ Roberts RJ (March 1980). "Restriction and modification enzymes and their recognition sequences". Gene 8 (4): 329–43. doi:10.1016/0378-1119(80)90040-2. PMID 6245015. 
  62. ↑ 62.0 62.1 "Actinobacillus and Streptococcus: producers of isoschizomers of the restriction endonucleases R.HphI, R.SauI, R.NheI, R.MboI and R.SwaI". Biol Chem 379 (4–5): 573–4. April–May 1998. PMID 9628357. 
  63. ↑ 63.0 63.1 "Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120". DNA Res 8 (5): 227–53. October 2001. doi:10.1093/dnares/8.5.205. PMID 11759840. 
  64. ↑ 64.0 64.1 "The nucleotide sequences recognized by endonucleases AvaI and AvaII from Anabaena variabilis". Biochem J 185 (1): 65–75. January 1980. doi:10.1042/bj1850065. PMID 6246881. 
  65. ↑ "Purification, properties and recognition sequence of site-specific restriction endonuclease from "Acetobacter xylinus"". Agric Biol Chem 47 (12): 2871–9. 1983. doi:10.1271/bbb1961.47.2871. 



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