Biology:Methanobrevibacter oralis
| Methanobrevibacter oralis | |
|---|---|
Scientific classification 
| |
| Domain: | Archaea |
| Kingdom: | Euryarchaeota |
| Class: | Methanobacteria |
| Order: | Methanobacteriales |
| Family: | Methanobacteriaceae |
| Genus: | Methanobrevibacter |
| Species: | M. oralis
|
| Binomial name | |
| Methanobrevibacter oralis Ferrari et al. 1995
| |
Methanobrevibacter oralis is a methanogenic archaeon species considered to be a member of the human microbiota, mainly associated to the oral cavity. M. oralis is a coccobacillary shaped, single-cell, Gram-positive, non-motile microorganism of the Archaea domain of life.[1] This species has been isolated and sequenced from humans in dental plaque and in their gastrointestinal tract.[1][2] As a methanogen and a hydrogenotroph, this prokaryote can produce methane by using hydrogen and carbon dioxide as substrates through a process called methanogenesis.
Discovery and comparisons to Methanobrevibacter smithii
Originally isolated in 1994 from human dental plaque, Methanobrevibacter oralis has been the third most common methanogenic archaea seen in the human body, preceded by Methanobrevibacter smithii and Methanosphaera stadtmanae. This species of archaea has not been described in an other animal species, only humans so far.[3] It has been seen in ancient human dental calculus, as well as in different studies of oral pathologies in different continents, from Europe, Asia, the America's and Africa.[4][5]
The first draft genomic sequence, however, came from a strain that came from stool.[6] This species is highly phylogenetically related to M. smithii however it is not a distinct member of the human gut, instead it is most prevalent in the human oral cavity. Comparisons of their genomic sequences shows distinct gene differences between the two species that may provide some information on the niche distinction. Another difference that separates M. oralis from M. smithii is that it only utilizes hydrogen gas (H2) and carbon dioxide (CO2) for methanogenesis, while M. smithii uses those two substrates as well as formate.[7]
Implications in oral health and human microbiome
The major interest with M. oralis has been that it is associated with periodontal disease, with an increase in abundance seen of this archaea when compared to its abundance in healthy samples. Periodontitis is an infection caused by multiple, different anaerobic bacteria and it has been suggested that the increase of M. oralis contributes to this disease due to potential syntrophic interactions with the other members of this infection.[8][9] These syntrophic interactions include supporting microbial fermentation by consuming the hydrogen from said process. Although not currently considered a pathogen for this disease, multiple studies are looking into understanding its relation to this disease through more cultivation-independent sample sets, evolutionary studies, and immunological responses.[5][10]
Although focus has been on the oral microbiome, PCR-based and metagenomic sequencing studies have been seeing evidence of this species in human gut, brain abscess, in the respiratory tract, and appendicular abscesses. More studies need to be done to understand the implication of M. oralis in these niches.[11][12][13]
References
- ↑ 1.0 1.1 Ferrari, Annamaria; Brusa, Tullio; Rutili, Anna; Canzi, Enrica; Biavati, Bruno (1994-07-01). "Isolation and characterization ofMethanobrevibacter oralis sp. nov." (in en). Current Microbiology 29 (1): 7–12. doi:10.1007/BF01570184. ISSN 1432-0991. https://doi.org/10.1007/BF01570184.
- ↑ Khelaifia, Saber; Garibal, Marc; Robert, Catherine; Raoult, Didier; Drancourt, Michel (2014-02-20). "Draft Genome Sequencing of Methanobrevibacter oralis Strain JMR01, Isolated from the Human Intestinal Microbiota". Genome Announcements 2 (1): e00073–14. doi:10.1128/genomeA.00073-14. ISSN 2169-8287. PMID 24558239.
- ↑ Guindo, Cheick Oumar; Davoust, Bernard; Drancourt, Michel; Grine, Ghiles (2020-12-23). "Diversity of Methanogens in Animals' Gut". Microorganisms 9 (1): 13. doi:10.3390/microorganisms9010013. ISSN 2076-2607. PMID 33374535.
- ↑ Granehäll, Lena; Huang, Kun D.; Tett, Adrian; Manghi, Paolo; Paladin, Alice; O’Sullivan, Niall; Rota-Stabelli, Omar; Segata, Nicola et al. (2021-09-30). "Metagenomic analysis of ancient dental calculus reveals unexplored diversity of oral archaeal Methanobrevibacter". Microbiome 9 (1): 197. doi:10.1186/s40168-021-01132-8. ISSN 2049-2618. PMID 34593021.
- ↑ 5.0 5.1 Sogodogo, Elisabeth; Doumbo, Ogobara; Aboudharam, Gérard; Kouriba, Bourema; Diawara, Ousseynou; Koita, Hapssa; Togora, Souleymane; Drancourt, Michel (2019-10-30). "First characterization of methanogens in oral cavity in Malian patients with oral cavity pathologies". BMC Oral Health 19 (1): 232. doi:10.1186/s12903-019-0929-8. ISSN 1472-6831. PMID 31666044.
- ↑ Khelaifia, Saber; Garibal, Marc; Robert, Catherine; Raoult, Didier; Drancourt, Michel (2014-02-27). "Draft Genome Sequencing of Methanobrevibacter oralis Strain JMR01, Isolated from the Human Intestinal Microbiota" (in en). Genome Announcements 2 (1). doi:10.1128/genomeA.00073-14. ISSN 2169-8287. PMID 24558239.
- ↑ Gaci, Nadia; Borrel, Guillaume; Tottey, William; O’Toole, Paul William; Brugère, Jean-François (2014-11-21). "Archaea and the human gut: New beginning of an old story". World Journal of Gastroenterology 20 (43): 16062–16078. doi:10.3748/wjg.v20.i43.16062. ISSN 1007-9327. PMID 25473158.
- ↑ Mohammadzadeh, Rokhsareh; Mahnert, Alexander; Duller, Stefanie; Moissl-Eichinger, Christine (2022-06-01). "Archaeal key-residents within the human microbiome: characteristics, interactions and involvement in health and disease". Current Opinion in Microbiology 67: 102146. doi:10.1016/j.mib.2022.102146. ISSN 1369-5274. PMID 35427870.
- ↑ Chaudhary, Prem Prashant; Conway, Patricia Lynne; Schlundt, Jørgen (2018-04-01). "Methanogens in humans: potentially beneficial or harmful for health" (in en). Applied Microbiology and Biotechnology 102 (7): 3095–3104. doi:10.1007/s00253-018-8871-2. ISSN 1432-0614. PMID 29497795. https://doi.org/10.1007/s00253-018-8871-2.
- ↑ Hirai, Kimito; Maeda, Hiroshi; Omori, Kazuhiro; Yamamoto, Tadashi; Kokeguchi, Susumu; Takashiba, Shogo (2013). ""Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT"". Pathogens and Disease 68 (1): 12–19. doi:10.1111/2049-632X.12041. PMID 23620386.
- ↑ Djemai, K.; Gouriet, F.; Sielezneff, I.; Mege, D.; Drancourt, M.; Grine, G. (2021-12-01). "Detection of methanogens in peri-appendicular abscesses: Report of four cases". Anaerobe 72: 102470. doi:10.1016/j.anaerobe.2021.102470. ISSN 1075-9964. PMID 34743984.
- ↑ Drancourt, Michel; Nkamga, Vanessa Demonfort; Lakhe, Ndèye Aïssatou; Régis, Jean-Marie; Dufour, Henry; Fournier, Pierre-Edouard; Bechah, Yassina; Michael Scheld, W et al. (2017-07-01). "Evidence of Archaeal Methanogens in Brain Abscess" (in en). Clinical Infectious Diseases 65 (1): 1–5. doi:10.1093/cid/cix286. ISSN 1058-4838. PMID 28379309. http://academic.oup.com/cid/article/65/1/1/3098386/Evidence-of-Archaeal-Methanogens-in-Brain-Abscess.
- ↑ Koskinen, Kaisa; Pausan, Manuela R.; Perras, Alexandra K.; Beck, Michael; Bang, Corinna; Mora, Maximilian; Schilhabel, Anke; Schmitz, Ruth et al. (2017-12-29). Schleper, Christa M.; Jansson, Janet K.. eds. "First Insights into the Diverse Human Archaeome: Specific Detection of Archaea in the Gastrointestinal Tract, Lung, and Nose and on Skin" (in en). mBio 8 (6). doi:10.1128/mBio.00824-17. ISSN 2161-2129. PMID 29138298.
Further reading
- Lepp, P. W.; Brinig, M. M.; Ouverney, C. C.; Palm, K.; Armitage, G. C.; Relman, D. A. (2004). "Methanogenic Archaea and human periodontal disease". Proceedings of the National Academy of Sciences 101 (16): 6176–6181. doi:10.1073/pnas.0308766101. ISSN 0027-8424. PMID 15067114. Bibcode: 2004PNAS..101.6176L.
- Horz HP, Conrads G. "Methanogenic Archaea and oral infections - ways to unravel the black box". J Oral Microbiol. 2011 Feb 23;3. doi: 10.3402/jom.v3i0.5940. PMID 21541092; PMCID: PMC 3086593.
- Vianna ME, Conrads G, Gomes BP, Horz HP. "Identification and quantification of archaea involved in primary endodontic infections". J Clin Microbiol. 2006 Apr;44(4):1274-82. doi: 10.1128/JCM.44.4.1274-1282.2006. PMID 16597851; PMCID: PMC1448633.
- Vianna ME, Holtgraewe S, Seyfarth I, Conrads G, Horz HP. "Quantitative analysis of three hydrogenotrophic microbial groups, methanogenic archaea, sulfate-reducing bacteria, and acetogenic bacteria, within plaque biofilms associated with human periodontal disease". J Bacteriol. 2008 May;190(10):3779-85. doi: 10.1128/JB.01861-07. Epub 2008 Mar 7. PMID 18326571; PMCID: PMC2394984.
- Weyrich, L., Duchene, S., Soubrier, J. et al. "Neanderthal behaviour, diet, and disease inferred from ancient DNA in dental calculus". Nature. 2017 Apr 20;544(7650):357-361. doi: 10.1038/nature21674. Epub 2017 Mar 8. PMID 28273061.
- Belkacemi S, Mazel A, Tardivo D, Tavitian P, Stephan G, Bianca G, Terrer E, Drancourt M, Aboudharam G. "Peri-implantitis-associated methanogens: a preliminary report". Sci Rep. 2018 Jun 21;8(1):9447. doi: 10.1038/s41598-018-27862-8. PMID 29930395; PMCID: PMC6013440.
External links
Wikidata ☰ Q18344101 entry
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