Biology:N-succinylornithine carbamoyltransferase
From HandWiki
| N-succinylornithine carbamoyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.3.11 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
N-succinylornithine carbamoyltransferase (EC 2.1.3.11, succinylornithine transcarbamylase, N-succinyl-L-ornithine transcarbamylase, SOTCase) is an enzyme with systematic name carbamoyl phosphate:N2-succinyl-L-ornithine carbamoyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- carbamoyl phosphate + N2-succinyl-L-ornithine [math]\displaystyle{ \rightleftharpoons }[/math] phosphate + N-succinyl-L-citrulline
This enzyme is specific for N-succinyl-L-ornithine.
References
- ↑ "Structure and catalytic mechanism of a novel N-succinyl-L-ornithine transcarbamylase in arginine biosynthesis of Bacteroides fragilis". The Journal of Biological Chemistry 281 (29): 20623–31. July 2006. doi:10.1074/jbc.M601229200. PMID 16704984.
- ↑ "A single mutation in the active site swaps the substrate specificity of N-acetyl-L-ornithine transcarbamylase and N-succinyl-L-ornithine transcarbamylase". Protein Science 16 (8): 1689–99. August 2007. doi:10.1110/ps.072919907. PMID 17600144.
External links
- N-succinylornithine+carbamoyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
 |  |
