Biology:PAFAH1B3

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Platelet-activating factor acetylhydrolase IB subunit gamma is an enzyme that in humans is encoded by the PAFAH1B3 gene.[1][2]

Interactions

PAFAH1B3 has been shown to interact with PAFAH1B1[3] and LNX1.[4]

See also

References

  1. "cDNA cloning of human cytosolic platelet-activating factor acetylhydrolase gamma-subunit and its mRNA expression in human tissues". Biochemical and Biophysical Research Communications 214 (1): 180–7. Sep 1995. doi:10.1006/bbrc.1995.2272. PMID 7669037. 
  2. "Entrez Gene: PAFAH1B3 platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5050. 
  3. "Lissencephaly associated mutations suggest a requirement for the PAFAH1B heterotrimeric complex in brain development". Mechanisms of Development 92 (2): 263–71. Apr 2000. doi:10.1016/S0925-4773(00)00242-2. PMID 10727864. 
  4. "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. Oct 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode2005Natur.437.1173R. 

Further reading

  • "The beta and gamma subunits of the human platelet-activating factor acetyl hydrolase isoform Ib (PAFAH1B2 and PAFAH1B3) map to chromosome 11q23 and 19q13.1, respectively". Genomics 51 (1): 157–9. Jul 1998. doi:10.1006/geno.1998.5322. PMID 9693049. 
  • "Lissencephaly associated mutations suggest a requirement for the PAFAH1B heterotrimeric complex in brain development". Mechanisms of Development 92 (2): 263–71. Apr 2000. doi:10.1016/S0925-4773(00)00242-2. PMID 10727864. 
  • "Preparation and crystal structure of the recombinant alpha(1)/alpha(2) catalytic heterodimer of bovine brain platelet-activating factor acetylhydrolase Ib". Protein Engineering 14 (7): 513–9. Jul 2001. doi:10.1093/protein/14.7.513. PMID 11522926. 
  • "Screening of Hsp105alpha-binding proteins using yeast and bacterial two-hybrid systems". Biochemical and Biophysical Research Communications 314 (2): 396–402. Feb 2004. doi:10.1016/j.bbrc.2003.12.108. PMID 14733918. 
  • "A human protein-protein interaction network: a resource for annotating the proteome". Cell 122 (6): 957–68. Sep 2005. doi:10.1016/j.cell.2005.08.029. PMID 16169070. 
  • "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. Oct 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode2005Natur.437.1173R. 
  • "Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress". Biochemical and Biophysical Research Communications 337 (4): 1308–18. Dec 2005. doi:10.1016/j.bbrc.2005.09.191. PMID 16236267.