Biology:PRPF19
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 Generic protein structure example |
Pre-mRNA-processing factor 19 is a protein that in humans is encoded by the PRPF19 gene.[1][2]
In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM][2]
Interactions
PRPF19 has been shown to interact with CDC5L.[3]
References
- ↑ Mahajan KN, Mitchell BS (September 2003). "Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase". Proc Natl Acad Sci U S A 100 (19): 10746–51. doi:10.1073/pnas.1631060100. PMID 12960389. Bibcode: 2003PNAS..10010746M.
- ↑ 2.0 2.1 "Entrez Gene: PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27339.
- ↑ Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMID 11101529.
Further reading
- "Reassembling proteins and chaperones in human nuclear matrix protein fractions.". J. Cell. Biochem. 74 (2): 145–51. 1999. doi:10.1002/(SICI)1097-4644(19990801)74:2<145::AID-JCB1>3.0.CO;2-#. PMID 10404385.
- "hNMP 200: a novel human common nuclear matrix protein combining structural and regulatory functions.". Exp. Cell Res. 261 (1): 166–79. 2000. doi:10.1006/excr.2000.5025. PMID 11082287.
- "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1–11. 2002. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
- "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.". RNA 8 (4): 426–39. 2002. doi:10.1017/S1355838202021088. PMID 11991638.
- "Functional proteomic analysis of human nucleolus.". Mol. Biol. Cell 13 (11): 4100–9. 2003. doi:10.1091/mbc.E02-05-0271. PMID 12429849.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing.". EMBO J. 23 (12): 2381–91. 2004. doi:10.1038/sj.emboj.7600241. PMID 15175653.
- "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436–50. 2004. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. 2005. doi:10.1038/nature03207. PMID 15635413. Bibcode: 2005Natur.433...77A.
- "Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome.". Biochem. J. 388 (Pt 2): 593–603. 2005. doi:10.1042/BJ20041517. PMID 15660529.
- "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links.". J. Biol. Chem. 280 (49): 40559–67. 2006. doi:10.1074/jbc.M508453200. PMID 16223718.
- "SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly.". Nucleic Acids Res. 33 (21): 6868–83. 2005. doi:10.1093/nar/gki986. PMID 16332694.
- "SNEV overexpression extends the life span of human endothelial cells.". Exp. Cell Res. 312 (6): 746–59. 2006. doi:10.1016/j.yexcr.2005.11.025. PMID 16388800.
- Lu X, Legerski RJ (2007). "The Prp19/Pso4 core complex undergoes ubiquitylation and structural alterations in response to DNA damage.". Biochem. Biophys. Res. Commun. 354 (4): 968–74. doi:10.1016/j.bbrc.2007.01.097. PMID 17276391.
- "Early embryonic lethality of mice lacking the essential protein SNEV.". Mol. Cell. Biol. 27 (8): 3123–30. 2007. doi:10.1128/MCB.01188-06. PMID 17283042.
- "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. 2007. doi:10.1038/msb4100134. PMID 17353931.
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