Biology:Presilphiperfolanol synthase
From HandWiki
| Presilphiperfolanol synthase | |||||||||
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| Identifiers | |||||||||
| EC number | 4.2.3.74 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Presilphiperfolanol synthase (EC 4.2.3.74, BcBOT2, CND15) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase (presilphiperfolan-8β-ol-forming).[1][2] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] presilphiperfolan-8β-ol + diphosphate
This enzyme requires Mg2+.
References
- ↑ "Sesquiterpene synthase from the botrydial biosynthetic gene cluster of the phytopathogen Botrytis cinerea". ACS Chem. Biol. 3 (12): 791–801. 2008. doi:10.1021/cb800225v. PMID 19035644.
- ↑ "Biosynthesis of the sesquiterpene botrydial in Botrytis cinerea. Mechanism and stereochemistry of the enzymatic formation of presilphiperfolan-8β-ol". J. Am. Chem. Soc. 131 (24): 8360–1. 2009. doi:10.1021/ja9021649. PMID 19476353.
External links
- Presilphiperfolanol+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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