Biology:Pyrrole-2-carboxylate decarboxylase

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Pyrrole-2-carboxylate decarboxylase
Identifiers
EC number4.1.1.93
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Pyrrole-2-carboxylate decarboxylase (EC 4.1.1.93) is an enzyme with systematic name pyrrole-2-carboxylate carboxy-lyase.[1][2][3] This enzyme catalyses the following chemical reaction

(1) pyrrole-2-carboxylate [math]\displaystyle{ \rightleftharpoons }[/math] pyrrole + CO2
(2) pyrrole-2-carboxylate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] pyrrole + HCO3

The enzyme catalyses both the carboxylation and decarboxylation reactions.

References

  1. "Carbon dioxide fixation by reversible pyrrole-2-carboxylate decarboxylase from Bacillus megaterium PYR2910". European Journal of Biochemistry 257 (2): 495–9. October 1998. doi:10.1046/j.1432-1327.1998.2570495.x. PMID 9826198. 
  2. "Pyrrole-2-carboxylate decarboxylase from Bacillus megaterium PYR2910, an organic-acid-requiring enzyme". European Journal of Biochemistry 253 (2): 480–4. April 1998. doi:10.1046/j.1432-1327.1998.2530480.x. PMID 9654100. 
  3. Wieser, M.; Yoshida, T.; Nagasawa, T. (1998). "Microbial synthesis of pyrrole-2-carboxylate by Bacillus megaterium PYR2910". Tetrahedron Lett. 39: 4309–4310. doi:10.1016/s0040-4039(98)00718-7. 

External links