Biology:Sabinene-hydrate synthase
From HandWiki
| sabinene-hydrate synthase | |||||||||
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| Identifiers | |||||||||
| EC number | 4.2.3.11 | ||||||||
| CAS number | 166800-09-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme sabinene-hydrate synthase (EC 4.2.3.11) catalyzes the chemical reaction
- geranyl diphosphate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] sabinene hydrate + diphosphate
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming). This enzyme is also called sabinene hydrate cyclase. This enzyme participates in monoterpenoid biosynthesis.
References
- "Monoterpene biosynthesis: demonstration of a geranyl pyrophosphate:sabinene hydrate cyclase in soluble enzyme preparations from sweet marjoram (Majorana hortensis)". Arch. Biochem. Biophys. 264 (2): 618–31. 1988. doi:10.1016/0003-9861(88)90328-1. PMID 3401015.
- "Monoterpene biosynthesis: mechanism and stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (+)-cis- and (+)-trans-sabinene hydrate". Arch. Biochem. Biophys. 269 (1): 313–26. 1989. doi:10.1016/0003-9861(89)90113-6. PMID 2916845.
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