Biology:Succinate—hydroxymethylglutarate CoA-transferase
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Short description: Class of enzymes
| Succinate-hydroxymethylglutarate CoA-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.8.3.13 | ||||||||
| CAS number | 80237-90-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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Succinate-hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) is an enzyme that catalyzes the chemical reaction
- REDIRECT Template:Chemical reaction
The two substrates of this enzyme characterised from rat liver are meglutol and succinic-CoA. Its products are HMG-CoA and succinic acid.[1][2]
This enzyme is a transferase, specifically a CoA-transferase. The systematic name of this enzyme class is succinyl-CoA:3-hydroxy-3-methylglutarate CoA-transferase. Other names in common use include hydroxymethylglutarate coenzyme A-transferase, and dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase.[3]
References
- ↑ "Submitochondrial localization and partial purification of the succinylCoA: 3-hydroxy-3-methylglutarate coenzyme A transferase from rat liver". Biochim. Biophys. Acta 662 (1): 119–24. 1981. doi:10.1016/0005-2744(81)90231-x. PMID 6946836.
- ↑ Schomburg, Dietmar; Stephan, Dörte (1997). "Succinate-hydroxymethylglutarate CoA-transferase". Enzyme Handbook. pp. 1089–1093. doi:10.1007/978-3-642-59025-2_207. ISBN 978-3-642-47773-7.
- ↑ Enzyme 2.8.3.18 at KEGG Pathway Database.
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