Biology:Tirucalladienol synthase

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Tirucalladienol synthase
Identifiers
EC number5.4.99.56
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Tirucalladienol synthase (EC 5.4.99.56, PEN3) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, tirucalla-7,24-dien-3beta-ol-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene [math]\displaystyle{ \rightleftharpoons }[/math] tirucalla-7,24-dien-3beta-ol

The product from Arabidopsis thaliana is tirucalla-7,24-dien-3beta-ol.

References

  1. "Product profile of PEN3: the last unexamined oxidosqualene cyclase in Arabidopsis thaliana". Organic Letters 11 (12): 2627–30. June 2009. doi:10.1021/ol9005745. PMID 19445469. 

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