Biology:Trans-2-decenoyl-(acyl-carrier protein) isomerase
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Trans-2-decenoyl-(acyl-carrier protein) isomerase | |||||||||
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Identifiers | |||||||||
EC number | 5.3.3.14 | ||||||||
CAS number | 9030-80-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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In enzymology, a trans-2-decenoyl-[acyl-carrier protein] isomerase (EC 5.3.3.14) is an enzyme that catalyzes the chemical reaction
- trans-dec-2-enoyl-[acyl-carrier-protein] [math]\displaystyle{ \rightleftharpoons }[/math] cis-dec-3-enoyl-[acyl-carrier-protein]
Hence, this enzyme has one substrate, trans-dec-2-enoyl-[acyl-carrier-protein], and one product, cis-dec-3-enoyl-[acyl-carrier-protein].
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is decenoyl-[acyl-carrier-protein] Delta2-trans-Delta3-cis-isomerase. Other names in common use include beta-hydroxydecanoyl thioester dehydrase, trans-2-cis-3-decenoyl-ACP isomerase, trans-2,cis-3-decenoyl-ACP isomerase, trans-2-decenoyl-ACP isomerase, and FabM.
References
- "Beta-hydroxydecanoyl thioester dehydrase. II. Mode of action". J. Biol. Chem. 242 (19): 4432–40. 1967. PMID 4863740.
- Bloch K (1969). "Enzymatic synthesis of monounsaturated fatty acids". Acc. Chem. Res. 2 (7): 193–202. doi:10.1021/ar50019a001.
- "A new mechanism for anaerobic unsaturated fatty acid formation in Streptococcus pneumoniae". J. Biol. Chem. 277 (47): 44809–16. 2002. doi:10.1074/jbc.M208920200. PMID 12237320.
- Neidhardt, F.C. (Ed.), Escherichia coli and Salmonella: Cellular and Molecular Biology, 2nd ed., vol. 1, ASM Press, Washington, DC, 1996, p. 612-636.
![]() | Original source: https://en.wikipedia.org/wiki/Trans-2-decenoyl-(acyl-carrier protein) isomerase.
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