Chemistry:Aceglatone

Short description: Antineoplastic drug available in Japan

Aceglatone

Clinical data
Trade names	Glucaron
Other names	D-Glucaric acid di-γ-lactone 2,5-diacetate 2,5-Di-O-acetyl-D-glucaro-1,4:6,3-dilactone 2,5-Di-O-acetyl-D-glucosaccharo-1,4:6,3-dilactone
AHFS/Drugs.com	International Drug Names
ATC code	none
Identifiers
IUPAC name (3R,3aR,6S,6aR)-2,5-Dioxohexahydrofuro[3,2-b]furan-3,6-diyl diacetate
CAS Number	642-83-1 N
PubChem CID	636372
ChemSpider	599998 Y
UNII	347Q3OOJ13
ChEMBL	ChEMBL2103781 N
Chemical and physical data
Formula	C10H10O8
Molar mass	258.182 g·mol−1
3D model (JSmol)	Interactive image
Melting point	185 to 186 °C (365 to 367 °F)
SMILES O=C1O[C@H]2[C@@H](OC(=O)C)C(=O)O[C@H]2[C@@H]1OC(=O)C
InChI InChI=1S/C10H10O8/c1-3(11)15-7-5-6(18-9(7)13)8(10(14)17-5)16-4(2)12/h5-8H,1-2H3/t5-,6-,7-,8+/m1/s1 Y Key:ZOZKYEHVNDEUCO-XUTVFYLZSA-N Y
NY (what is this?)  (verify)

Aceglatone (Glucaron) is an antineoplastic drug available in Japan.

It is an inhibitor of the enzyme β-glucuronidase.