Chemistry:Chlorphoxim

From HandWiki
Chlorphoxim
Chlorphoxim Structural Formula.svg
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
EC Number
  • 238-888-9
KEGG
UNII
Properties
C12H14ClN2O3PS
Molar mass 332.74 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Chlorphoxime is an insecticide used as crop protection active ingredient.[1] Chlorphoxime is also a cholinesterase inhibitor and a neurotoxin.[2]

Properties

A study was conducted to investigate the effect of chlorophoxime for the control of fleas in kangaroo rats and hispid cotton rats. Chlorphoxime was found to be effective.[3]

In another study, the efficacy of some insecticides was investigated on certain storage pests. While phoxim, bioresmethrin and fenitrothion showed strong activity against the red-brown rice mealybug, the insecticidal activity of chlorphoxim and permethrin was low.[4]

Production

The synthesis of chlorophoxime is described in the following reaction sequence:[1]

Chlorphoxim synthesis

Trade names

A crop protection product containing the active ingredient chlorophoxime is marketed under the trade name Baythion.[1]

Approval

No plant protection products containing chlorophoxime are approved in the European Union or Switzerland.[5]

References

  1. 1.0 1.1 1.2 Thomas A. Unger (1996), "Chlorphoxim" (in German), Pesticide Synthesis Handbook (Elsevier): p. 312, doi:10.1016/b978-081551401-5.50240-9, ISBN 978-0-8155-1401-5 
  2. University of Hertfordshire. "Chlorphoxim (Ref: OMS 1197)". http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/1290.htm. 
  3. Bryan E. Miller, William. C. Bennett, Garth N. Graves, John R. Wheeler (1977-11-25), "Field Studies of Systemic Insecticides. II. Evaluation of chlorphoxim for control of fleas on five rodent species12" (in German), Journal of Medical Entomology 14 (2): pp. 161–166, doi:10.1093/jmedent/14.2.161, ISSN 1938-2928, PMID 606815 
  4. M. A. Khan (1983-02-01), "Wirksamkeit von Insektiziden und Repellents gegen Vorratsschädlinge" (in German), Anzeiger für Schädlingskunde, Pflanzenschutz, Umweltschutz 56 (2): pp. 25–29, doi:10.1007/BF01905984, ISSN 1612-4766 
  5. European Commission Directorate-General for Health and Food Safety: EU Pesticides Database; entry in the national plant protection product inventories of Switzerland, Austria and Germany, accessed July 20, 2022.