Chemistry:Damnacanthal
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| Names | |
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| Preferred IUPAC name
3-Hydroxy-1-methoxy-9,10-dioxo-9,10-dihydroanthracene-2-carbaldehyde | |
| Other names
3-Hydroxy-1-methoxyanthraquinone-2-aldehyde
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C16H10O5 | |
| Molar mass | 282.251 g·mol−1 |
| Density | 1.461 g/mL |
| Boiling point | 532 °C (990 °F; 805 K) |
| Related compounds | |
Related arylformaldehydes
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Gossypol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Infobox references | |
Damnacanthal is an anthraquinone isolated from the root of Morinda citrifolia, using water[1] or organic solvents.[2]
Pharmacology
In a 1995 in vitro study, damnacanthal was found to act as a potent and selective inhibitor of p56lck tyrosine kinase.[3]
References
- ↑ "Extraction of anti-cancer damnacanthal from roots of Morinda citrifolia by subcritical water". Separation and Purification Technology 55 (3): 343–349. July 2007. doi:10.1016/j.seppur.2007.01.004.
- ↑ "The antinociceptive and anti-inflammatory action of the CHCl3-soluble phase and its main active component, damnacanthal, isolated from the root of Morinda citrifolia". Biol Pharm Bull 34 (1): 103–7. 2011. doi:10.1248/bpb.34.103. PMID 21212526.
- ↑ "Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity". Biochemistry 34 (38): 12404–10. September 1995. doi:10.1021/bi00038a038. PMID 7547985.
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