Chemistry:Iotroxic acid
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| Trade names | Biliscopin, others |
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| Formula | C22H18I6N2O9 |
| Molar mass | 1215.818 g·mol−1 |
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Iotroxic acid (trade name Biliscopin), used in the form of meglumine iotroxate, is a molecule used as a contrast medium during X-rays.[1][2] It is specifically used during tests looking at the gallbladder and biliary tract.[2] It is given by slow injection into a vein.[2]
Side effects are uncommon.[3] They include vomiting, skin flushing, headache, itchiness, and low blood pressure.[2] Rare side effects include seizures and allergic reactions.[2] It should not be used by those who have an iodine allergy.[2] Iotroxic acid is an iodine containing contrast media of the diionic dimer type.[4]
Iotroxic acid was first made in 1976.[5] It is on the World Health Organization's List of Essential Medicines.[6] It is rarely used in the developed world due to the availability of magnetic resonance cholangiopancreatography (MRCP).[7]
References
- ↑ "Iotroxic Acid". Drugs.com. https://www.drugs.com/international/iotroxic-acid.html.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 WHO Model Formulary 2008. World Health Organization. 2009. pp. 315, 318. ISBN 9789241547659.
- ↑ "Diagnosis and treatment of common bile duct stones" (in en). Recommendations for evidence-based endoscopic surgery: The updated EAES consensus development conferences. Springer Science & Business Media. 2014. p. 67. ISBN 9782817808499. https://books.google.com/books?id=seILBwAAQBAJ&pg=PA67.
- ↑ "Iodine containing contrast media" (in en). Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment. Academic Press. 2014. p. 532. ISBN 9780124079014. https://books.google.com/books?id=L2NzAwAAQBAJ&pg=PA532.
- ↑ (in en) Essentials of Medicinal Chemistry. Wiley. 1988. p. 1063. ISBN 9780471883562. https://books.google.com/books?id=6hxtAAAAMAAJ.
- ↑ World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. 2019. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ↑ "Imaging of the Biliary Tract: Interventional Radiology and Endoscopy" (in en). Diseases of the Liver and Biliary System. John Wiley & Sons. 2008. p. 568. ISBN 9780470986813. https://books.google.com/books?id=-TD1_-SiqvcC&pg=PA568.
External links
- "Iotroxic Acid". Drug Information Portal. U.S. National Library of Medicine. https://druginfo.nlm.nih.gov/drugportal/name/iotroxic%20acid.
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