Chemistry:Perflubron
From HandWiki
Short description: Chemical compound
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| Formula | C8BrF17 |
| Molar mass | 498.965 g·mol−1 |
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| Density | 1.93 g/cm3 |
| Melting point | 6 °C (43 °F) |
| Boiling point | 142 °C (288 °F) |
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Perflubron (INN/USAN, or perfluorooctyl bromide; brand name Imagent) is a contrast medium for magnetic resonance imaging, computer tomography and sonography.[1] It was approved for this use in the United States by the Food and Drug Administration in 1993.[2]
Experimental research
Perflubron has also been tested experimentally for use in liquid breathing in premature infants with respiratory distress.[3][4]
References
- ↑ "Perfluorooctylbromide: a new contrast agent for CT, sonography, and MR imaging". AJR. American Journal of Roentgenology 152 (2): 247–52. February 1989. doi:10.2214/ajr.152.2.247. PMID 2643258.
- ↑ FDA Approved Drug Products
- ↑ "Perfluorochemical rescue after surfactant treatment: effect of perflubron dose and ventilatory frequency". Journal of Applied Physiology 84 (2): 624–40. February 1998. doi:10.1152/jappl.1998.84.2.624. PMID 9475875.
- ↑ "Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome. The LiquiVent Study Group". The New England Journal of Medicine 335 (11): 761–7. September 1996. doi:10.1056/NEJM199609123351101. PMID 8778584.
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